trans-humulinic acid

Base Information

• Chemical Name: trans-humulinic acid
• CAS No.: 24184-13-2
• Molecular Formula: C₁₅H₂₂O₄
• Molecular Weight: 266.337
• Mol file: 24184-13-2.mol

Synonyms:trans-humulinic acid

Chemical Property of trans-humulinic acid

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of trans-humulinic acid

There total 4 articles about trans-humulinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trans-isohumulone (467-72-1) + L-proline (147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7) → 3-methylbutyric acid (503-74-2) + 4-methyl-pent-3-enoic acid (504-85-8) + trans-humulinic acid (24184-13-2) + 4-hydroxy-trans-alloisohumulone (1233663-81-4) + 1-(3-methylbutanoyl)-L-proline (55817-63-5)

Guidance literature:

With air; In aq. phosphate buffer; ethanol; at 50 ℃; for 504h; pH=7; pH-value; Reagent/catalyst;

DOI:10.1021/jf501826h

Reference yield:

trans-isohumulone (467-72-1) → 4-methyl-pent-3-enoic acid (504-85-8) + trans-humulinic acid (24184-13-2) + 4-hydroxy-trans-alloisohumulone (1233663-81-4) + trans-3-methylbutyric acid L-proline amide + trans-4-methyl-3-pentenoic acid L-proline amide + butyric acid (107-92-6)

Guidance literature:

With water; for 504h; pH-value; Reagent/catalyst; Acidic conditions;

DOI:10.1021/jf501826h

Reference yield:

humulone (26472-41-3) → (+/-)-3,4r-dihydroxy-2-isovaleryl-5t-(3-methyl-but-2-enyl)-cyclopent-2-enone (24183-31-1,24184-08-5,24184-09-6,24184-12-1,24184-13-2,26892-78-4,38574-00-4,38574-22-0,92077-87-7)

Guidance literature:

With sodium hydroxide;

upstream raw materials:

trans-isohumulone

L-proline

humulone

Refernces

• 1、 Rakete, Stefan,Berger, Robert,B?hme, Steffi,Glomb, Marcus A.. "Oxidation of isohumulones induces the formation of carboxylic acids by hydrolytic cleavage". . p. 7541 - 7549. Retrieved 2015/04/22.