oxepan-2-yl acetate

Base Information

• Chemical Name: oxepan-2-yl acetate
• CAS No.: 106421-03-8
• Molecular Formula: C₈H₁₄O₃
• Molecular Weight: 158.197
• Mol file: 106421-03-8.mol

Synonyms:oxepan-2-yl acetate

Chemical Property of oxepan-2-yl acetate

Chemical Property:

Purity/Quality:

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Technology Process of oxepan-2-yl acetate

There total 1 articles about oxepan-2-yl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

1,6-hexanediol (629-11-8) + Dess-Martin periodane (87413-09-0) → oxepan-2-yl acetate (106421-03-8) + hexanedial (1072-21-5)

Guidance literature:

In dichloromethane; at 20 ℃; for 2h;

DOI:10.1055/s-2001-14610

Reference yield: 91.0%

oxepan-2-yl acetate (106421-03-8) + 1-<(tert-butyldimethylsilyl)oxy>-1-(benzyloxy)ethylene (92144-04-2) → benzyl (S)-2-(oxepan-2-yl)acetate

Guidance literature:

1-<(tert-butyldimethylsilyl)oxy>-1-(benzyloxy)ethylene; With N,N'-(azanediylbis(2,6-di-p-tolyl-4λ⁵-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine-4-yl-4-ylidene))bis(1,1,1-trifluoromethanesulfonamide); In toluene; at -78 - 20 ℃; for 0.166667h; Inert atmosphere;

oxepan-2-yl acetate; In toluene; at -78 ℃; for 16h; enantioselective reaction; Inert atmosphere;

DOI:10.1021/jacs.6b11993

Reference yield:

oxepan-2-yl acetate (106421-03-8) + (2,4-dinitro-phenyl)-hydrazine (119-26-6) → 6-hydroxy-hexanal-(2,4-dinitro-phenylhydrazone) (18843-56-6)

Guidance literature:

With acid solution;

DOI:10.1021/ja01545a040

upstream raw materials:

1,6-hexanediol

Dess-Martin periodane

Downstream raw materials:

6-hydroxy-hexanal-(2,4-dinitro-phenylhydrazone)

Refernces