Technology Process of C16H8Br2N2
There total 5 articles about C16H8Br2N2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium t-butanolate;
In
tetrahydrofuran;
for 10h;
Heating;
DOI:10.1021/ol034246v
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 95 percent / Zn / methanol / 4 h / 23 °C
2.1: 48 percent HBr / H2O / 2 h
2.2: NaNO2 / H2O
2.3: 72 percent / CuBr; 48 percent HBr / H2O / 2 h / Heating
3.1: 92 percent / NBS; BPO / CCl4 / 9 h / Heating
4.1: 58 percent / trimethylamine oxide / dimethylsulfoxide; CH2Cl2 / 8 h / 28 °C
5.1: 87 percent / t-BuONa / tetrahydrofuran / 10 h / Heating
With
N-Bromosuccinimide; trimethylamine-N-oxide; hydrogen bromide; sodium t-butanolate; zinc; dibenzoyl peroxide;
In
tetrahydrofuran; methanol; tetrachloromethane; dichloromethane; water; dimethyl sulfoxide;
5.1: HornerWadsworth-Emmons reaction;
DOI:10.1021/ol034246v
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 48 percent HBr / H2O / 2 h
1.2: NaNO2 / H2O
1.3: 72 percent / CuBr; 48 percent HBr / H2O / 2 h / Heating
2.1: 92 percent / NBS; BPO / CCl4 / 9 h / Heating
3.1: 58 percent / trimethylamine oxide / dimethylsulfoxide; CH2Cl2 / 8 h / 28 °C
4.1: 87 percent / t-BuONa / tetrahydrofuran / 10 h / Heating
With
N-Bromosuccinimide; trimethylamine-N-oxide; hydrogen bromide; sodium t-butanolate; dibenzoyl peroxide;
In
tetrahydrofuran; tetrachloromethane; dichloromethane; water; dimethyl sulfoxide;
4.1: HornerWadsworth-Emmons reaction;
DOI:10.1021/ol034246v