4,4'-Dihydroxybibenzyl

Base Information

• Chemical Name: 4,4'-Dihydroxybibenzyl
• CAS No.: 6052-84-2
• Molecular Formula: C14H14 O2
• Molecular Weight: 214.264
• Hs Code.: 2907299090
• NSC Number: 87365
• UNII: 3OXU6S6XEX
• DSSTox Substance ID: DTXSID7022461
• Nikkaji Number: J805.281F
• Wikidata: Q27116021
• Pharos Ligand ID: 1J1QWQ9KV7NX
• Metabolomics Workbench ID: 27983
• ChEMBL ID: CHEMBL577241
• Mol file: 6052-84-2.mol

Synonyms:4,4'-dihydroxybibenzyl

Chemical Property of 4,4'-Dihydroxybibenzyl

Chemical Property:

• Melting Point: 290℃ (decomposition)
• Boiling Point: 380.4oC at 760 mmHg
• Flash Point: 184.1oC
• PSA: 40.46000
• Density: 1.191g/cm3
• LogP: 2.88300
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 214.099379685
• Heavy Atom Count: 16
• Complexity: 167

Purity/Quality:

98% ^*data from raw suppliers

4-(4-HYDROXYPHENETHYL)BENZENOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1CCC2=CC=C(C=C2)O)O

Technology Process of 4,4'-Dihydroxybibenzyl

There total 23 articles about 4,4'-Dihydroxybibenzyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1,2-bis(4-methoxyphenyl)ethane (1657-55-2) → 4,4'-ethylenediphenol (6052-84-2)

Guidance literature:

1,2-bis(4-methoxyphenyl)ethane; With boron tribromide; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

With water; In dichloromethane; at 0 ℃;

DOI:10.1016/j.ejmech.2009.02.006

Reference yield: 97.0%

trans-4,4'-dihydroxystilbene (659-22-3,15058-36-3,29884-51-3) → 4,4'-ethylenediphenol (6052-84-2)

Guidance literature:

With hydrogen; 5% Pd/C; In methanol; ethyl acetate; for 2h;

Reference yield: 82.0%

1,2-bis(4-hydroxyphenyl)-ethane-1,2-diol (5173-27-3) + butan-1-ol (71-36-3) → 4,4'-ethylenediphenol (6052-84-2)

Guidance literature:

With carbon monoxide; hydrogen;

upstream raw materials:

1,2-bis(4-methoxyphenyl)ethane

4,4'-diaminodihydrostilbene

1,1'-(1,2-ethanediyl)bisbenzene

1-bromo-butane

Downstream raw materials:

p-cresol

1,2-bis(4-(prop-1-en-1-yloxy)phenyl)ethane

1-(2,2-diethyl-4-methylcyclobutoxy)-4-(4-(prop-1-en-1-yloxy)phenethyl)benzene

1,2-bis(4-(2,2-diethyl-4-methylcyclobutoxy)phenyl)ethane

Refernces

• 1、 -. "COMPOUNDS, COJUGATES AND COMPOSITIONS FOR USE IN THE METHODS FOR TRANS-MEMBRANE DELIVERY OF MOLECULES". Paragraph 00130. . Retrieved 2020/03/23.
• 2、 Dwivedi, Smriti,Singh, Pravin K.. "Synthesis and fungicidal activity of bioactive 4,4′-bis[4″-(N-benzylidinylamine)-3″-mercapto-1″,2″,4″-triazole-5″-yl methoxy]dibenzyl". . p. 19 - 21. Retrieved 2016/12/22.