14-hydroxycodeinone hydrochloride

Base Information

• Chemical Name: 14-hydroxycodeinone hydrochloride
• CAS No.: 5985-56-8
• Molecular Formula: C₁₈H₁₉NO₄*ClH
• Molecular Weight: 349.814
• Mol file: 5985-56-8.mol

Synonyms:14-hydroxycodeinone hydrochloride

Chemical Property of 14-hydroxycodeinone hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 14-hydroxycodeinone hydrochloride

There total 1 articles about 14-hydroxycodeinone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Oxycodone (76-42-6) + 14-hydroxycodeinone (508-54-3) → oxycodone hydrochloride (124-90-3) + 14-hydroxycodeinone hydrochloride (5985-56-8)

Guidance literature:

With hydrogenchloride; In water; isopropyl alcohol; at 20 - 75 ℃; Product distribution / selectivity;

Reference yield: 89.33%

oxycodone hydrochloride (124-90-3) + 14-hydroxycodeinone hydrochloride (5985-56-8) → Oxycodone (76-42-6)

Guidance literature:

oxycodone hydrochloride; 14-hydroxycodeinone hydrochloride; With hydrogen; 5%-palladium/activated carbon; In water; isopropyl alcohol; at 20 ℃; for 24h; under 620.594 Torr;

With sodium hydroxide; In water; isopropyl alcohol; at 0 - 5 ℃; for 1h; pH=9 - 10; Product distribution / selectivity;

Reference yield:

14-hydroxycodeinone hydrochloride (5985-56-8) → Oxycodone (76-42-6)

Guidance literature:

14-hydroxycodeinone hydrochloride; With formic acid; hydrogen; In methanol; at 80 ℃; for 20h; under 11251.1 Torr;

With sodium hydroxide; In methanol; water;

upstream raw materials:

Oxycodone

14-hydroxycodeinone

Downstream raw materials:

oxycodone hydrochloride

Oxycodone

Refernces