Phenanthro[4,5-bcd]furan-1-ol

Base Information

• Chemical Name: Phenanthro[4,5-bcd]furan-1-ol
• CAS No.: 519-56-2
• Molecular Formula: C14H8 O2
• Molecular Weight: 208.216
• DSSTox Substance ID: DTXSID90966227
• Mol file: 519-56-2.mol

Synonyms:SCHEMBL18117619;Phenanthro[4,5-bcd]furan-1-ol;DTXSID90966227

Chemical Property of Phenanthro[4,5-bcd]furan-1-ol

Chemical Property:

• Melting Point: 145°
• Boiling Point: 393.9°Cat760mmHg
• Flash Point: 192°C
• PSA: 33.37000
• Density: 1.453g/cm³
• LogP: 3.88260
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 208.052429494
• Heavy Atom Count: 16
• Complexity: 291

Purity/Quality:

99%, ^*data from raw suppliers

MORPHENOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C3C(=C1)OC4=C3C(=C(C=C4)O)C=C2

Technology Process of Phenanthro[4,5-bcd]furan-1-ol

There total 14 articles about Phenanthro[4,5-bcd]furan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

1,5,7-tri-t-butylphenanthro<4,5-bcd>furan-3-ol (94473-42-4) → morphenol (519-56-2)

Guidance literature:

With hydrogen bromide; zinc; In acetic acid; for 17h; Heating;

Reference yield:

3,5,3',5'-Tetra-tert-butyl-6,6'-dimethyl-biphenyl-2,2'-diol (6390-68-7) → morphenol (519-56-2)

Guidance literature:

Multi-step reaction with 7 steps

1: SOCl₂, pyridine

2: 1) Br₂, 2) Mg / 1) irradiation

3: 1) NBS, 2) KOAc, AcOH

4: LiAlH₄

5: PbO₂ / benzene

6: Zn, AcOH

7: HBr, Zn / acetic acid

With pyridine; N-Bromosuccinimide; lithium aluminium tetrahydride; thionyl chloride; hydrogen bromide; bromine; potassium acetate; lead dioxide; magnesium; acetic acid; zinc; In acetic acid; benzene;

DOI:10.1039/c39840001419

Reference yield:

1,11-dimethyl-2,4,8,10-tetra-t-butyldibenzo<1,3,2>dioxathiepine 6-oxide (94473-33-3) → morphenol (519-56-2)

Guidance literature:

Multi-step reaction with 6 steps

1: 1) Br₂, 2) Mg / 1) irradiation

2: 1) NBS, 2) KOAc, AcOH

3: LiAlH₄

4: PbO₂ / benzene

5: Zn, AcOH

6: HBr, Zn / acetic acid

With N-Bromosuccinimide; lithium aluminium tetrahydride; hydrogen bromide; bromine; potassium acetate; lead dioxide; magnesium; acetic acid; zinc; In acetic acid; benzene;

DOI:10.1039/c39840001419

upstream raw materials:

1,5,7-tri-t-butylphenanthro<4,5-bcd>furan-3-ol

3,5,3',5'-Tetra-tert-butyl-6,6'-dimethyl-biphenyl-2,2'-diol

1,3a,5,7-t-butylphenanthro<4,5-bcd>furan-3(3aH)-one

1,3,6,8-tetra-t-butylphenanthrene-4,5-diol

Downstream raw materials:

phenanthrene

Refernces

• 1、 Bucher, G?tz,Cioncoloni, Giacomo,Symes, Mark D.,Wilkinson, Dylan. "Attempted characterisation of phenanthrene-4,5-quinone and electrochemical synthesis of violanthrone-16,17-quinone. How does the stability of bay quinones correlate with structural and electronic parameters?". . p. 38004 - 38012. Retrieved 2020/11/02.