Technology Process of C29H23BrN4O3S
There total 11 articles about C29H23BrN4O3S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
4-bromopyridine-3-carboxylic acid;
With
oxalyl dichloride;
N,N-dimethyl-formamide;
at 20 ℃;
for 0.0833333h;
C23H21N3O2S;
With
pyridine;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 0.0833333h;
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: trichlorophosphate / 5 h / 20 °C / Reflux
1.2: Cooling with ice
2.1: ethanol; sodium / 0.5 h / Cooling with ice
2.2: 3.5 h / 0 °C / Reflux
3.1: hydrogen bromide; acetic acid / Reflux
3.2: 6 h / Reflux
4.1: pyridine; HATU / 16 h / 20 °C / Inert atmosphere
5.1: pyridine / acetonitrile / 2 h / 20 °C / Inert atmosphere
6.1: hydrogenchloride; hydrogen / palladium 10% on activated carbon / ethanol; water / 2.33 h / 20 °C / Inert atmosphere
7.1: oxalyl dichloride / N,N-dimethyl-formamide / 0.08 h / 20 °C
7.2: 0.08 h / 20 °C
With
pyridine; hydrogenchloride; oxalyl dichloride; ethanol; hydrogen bromide; hydrogen; sodium; acetic acid; HATU; trichlorophosphate;
palladium 10% on activated carbon; N,N-dimethyl-formamide;
In
ethanol; water; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 9 steps
1.1: potassium carbonate / butanone, 1-
2.1: potassium tert-butylate / toluene
3.1: trichlorophosphate / 5 h / 20 °C / Reflux
3.2: Cooling with ice
4.1: ethanol; sodium / 0.5 h / Cooling with ice
4.2: 3.5 h / 0 °C / Reflux
5.1: hydrogen bromide; acetic acid / Reflux
5.2: 6 h / Reflux
6.1: pyridine; HATU / 16 h / 20 °C / Inert atmosphere
7.1: pyridine / acetonitrile / 2 h / 20 °C / Inert atmosphere
8.1: hydrogenchloride; hydrogen / palladium 10% on activated carbon / ethanol; water / 2.33 h / 20 °C / Inert atmosphere
9.1: oxalyl dichloride / N,N-dimethyl-formamide / 0.08 h / 20 °C
9.2: 0.08 h / 20 °C
With
pyridine; hydrogenchloride; oxalyl dichloride; ethanol; potassium tert-butylate; hydrogen bromide; hydrogen; sodium; potassium carbonate; acetic acid; HATU; trichlorophosphate;
palladium 10% on activated carbon; N,N-dimethyl-formamide;
In
ethanol; butanone, 1-; water; toluene; acetonitrile;
