Coumaphos

Base Information Edit

Chemical Name:Coumaphos
CAS No.:56-72-4
Molecular Formula:C14H16 Cl O5 P S
Molecular Weight:362.771
Hs Code.:
European Community (EC) Number:200-285-3
ICSC Number:0422
NSC Number:759838,8944
UN Number:3027,2783
UNII:L08SZ5Z5JC
DSSTox Substance ID:DTXSID2020347
Nikkaji Number:J4.573J
Wikipedia:Coumaphos
Wikidata:Q415896
NCI Thesaurus Code:C76867
Metabolomics Workbench ID:53093
ChEMBL ID:CHEMBL251680
Mol file:56-72-4.mol

Synonyms:Asuntol;Coumafos;Coumaphos

Suppliers and Price of Coumaphos

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Coumaphos
1g
$ 490.00

Sigma-Aldrich
Coumaphos PESTANAL
250mg
$ 84.30

Cayman Chemical
Coumaphos
100mg
$ 69.00

Cayman Chemical
Coumaphos
50mg
$ 39.00

AK Scientific
Coumaphos
250mg
$ 78.00

AHH
Coumaphos 98%
1g
$ 353.00

Total 2 raw suppliers

Chemical Property of Coumaphos Edit

Chemical Property:

Appearance/Colour:tan or beige solid
Vapor Pressure:2.76E-08mmHg at 25°C
Melting Point:91ºC
Refractive Index:1.577
Boiling Point:449.9 °C at 760 mmHg
Flash Point:225.9 °C
PSA：99.80000
Density:1.38 g/cm³
LogP:5.08170
Storage Temp.:APPROX 4°C
Water Solubility.:1.5 mg l-1 (20 °C)
XLogP3:4.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:362.0144595
Heavy Atom Count:22
Complexity:500
Transport DOT Label:Poison

Purity/Quality:

96% ^*data from raw suppliers

Coumaphos ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T+,N,Xn,F
Statements: 21-28-50/53-36-20/21/22-11
Safety Statements: 28-36/37-45-60-61-36-26-16

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Pesticides -> Organophosphate Insecticides
Canonical SMILES:CCOP(=S)(OCC)OC1=CC2=C(C=C1)C(=C(C(=O)O2)Cl)C
Inhalation Risk:Evaporation at 20 °C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered.
Effects of Short Term Exposure:Cholinesterase inhibition. The substance may cause effects on nervous system. The effects may be delayed. Medical observation is indicated.
Effects of Long Term Exposure:Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms.
Description Technical coumaphos is a tan crystalline solid with a slight sulphur odour. It is insoluble in water; slightly soluble in acetone, chloroform, and ethanol; and soluble in organic solvents. Coumaphos when heated undergoes decomposition and releases very toxic fumes of sulphur oxides, phosphorous oxides, and chlorides. It is used for the control of a wide variety of livestock insects, including cattle grubs, screwworms, lice, scabies, flies, and ticks. It is used against ectoparasites, which are insects that live on the outside of host animals such as sheep, goats, horses, pigs, and poultry. Coumaphos is incompatible with alkalis, strong oxidising agents, pyrethroids, and piperonyl butoxide. The U.S. EPA has grouped coumaphos as RUP.
Uses Coumaphos is used to control larvae of Diptera and ticks on cattle. It has also recently been used to control Varroa mite in honeybees.

Technology Process of Coumaphos

There total 3 articles about Coumaphos which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 2524-04-1
diethyl phosphorochloridothioate

: Sodium; 3-chloro-4-methyl-2-oxo-2H-chromen-7-olate

: 56-72-4
coumaphos

Guidance literature:: In N,N-dimethyl-formamide;

Reference yield: 58.0%

: 6174-86-3
3-chloro-4-methylumbelliferone

: 2524-04-1
diethyl phosphorochloridothioate

: 56-72-4
coumaphos

Guidance literature:: 3-chloro-4-methylumbelliferone; With n-butyllithium; In tetrahydrofuran; hexane; for 1h;

diethyl phosphorochloridothioate; In tetrahydrofuran; hexane; at 20 ℃; for 12h;
DOI:10.1021/jm050518j