Cyclo(Ile-Leu)

Base Information

• Chemical Name: Cyclo(Ile-Leu)
• CAS No.: 91741-17-2
• Molecular Formula: C₁₂H₂₂N₂O₂
• Molecular Weight: 226.319
• Mol file: 91741-17-2.mol

Synonyms:DL-isoleucyl-leucyl anhydride

Chemical Property of Cyclo(Ile-Leu)

Chemical Property:

• Boiling Point: 444.9±38.0 °C(Predicted)
• PKA: 13.27±0.60(Predicted)
• Density: 0.979±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

Cyclo(Ile-Leu) ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclo(Ile-Leu)

There total 6 articles about Cyclo(Ile-Leu) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3-sec-butyl-6-isobutyl-piperazine-2,5-dione (35590-82-0,35590-83-1,91741-17-2)

Guidance literature:

With β-naphthol; at 150 ℃; (3RS,6Ξ)-3-<(RS)-sec-butyl>-6-isobutyl-piperazine-2,5-dione, racemat of mp: 277 degree;

Reference yield:

N-(2-bromo-3-methyl-valeryl)-leucine → 3-sec-butyl-6-isobutyl-piperazine-2,5-dione (35590-82-0,35590-83-1,91741-17-2)

Guidance literature:

With hydrogenchloride; (3RS,6Ξ)-3-<(RS)-sec-butyl>-6-isobutyl-piperazine-2,5-dione, racemat of mp: 277 degree; anschl. mit NH₃ auf 140grad (bei den Edukten handelt es um Diastereomere);

Reference yield:

N-(2-bromo-4-methyl-valeryl)-isoleucine (909874-75-5) → 3-sec-butyl-6-isobutyl-piperazine-2,5-dione (35590-82-0,35590-83-1,91741-17-2)

Guidance literature:

With hydrogenchloride; (3RS,6Ξ)-3-<(RS)-sec-butyl>-6-isobutyl-piperazine-2,5-dione, racemat of mp: 277 degree; anschl. mit NH₃ auf 140grad (bei den Edukten handelt es um Diastereomere);

upstream raw materials:

N-(2-bromo-4-methyl-valeryl)-isoleucine

2-bromo-3-methyl-valeryl chloride

LEUCINE

N-leucyl-isoleucine

Downstream raw materials:

isoleucine

LEUCINE

dl-aspergillic acid