4-Amino-1-naphthol hydrochloride

Base Information

• Chemical Name: 4-Amino-1-naphthol hydrochloride
• CAS No.: 5959-56-8
• Molecular Formula: C10H9 N O . Cl H
• Molecular Weight: 195.648
• Hs Code.: 29222900
• European Community (EC) Number: 227-727-8
• NSC Number: 7943
• DSSTox Substance ID: DTXSID60884207
• Wikidata: Q27236581
• ChEMBL ID: CHEMBL1794195
• Mol file: 5959-56-8.mol

Synonyms:4-Amino-1-naphthol hydrochloride;5959-56-8;4-aminonaphthalen-1-ol Hydrochloride;4-Amino-1-naphthol HCl;1-Amino-4-naphthol hydrochloride;1-Naphthalenol, 4-amino-, hydrochloride;4-aminonaphthalen-1-ol;hydrochloride;UNII-0BK4F3B6ZX;PCMD-CC-PAB-253;1-Naphthalenol, 4-amino-, hydrochloride (1:1);NSC-7943;PC-0685415;MFCD00012562;4-Amino-1-hydroxynaphthalene hydrochloride;MLS001045587;SCHEMBL295131;CHEMBL1794195;4-Amino-1-naphtol hydrochloride;DTXSID60884207;NSC7943;FDBQTRARWCKEJY-UHFFFAOYSA-N;AMY24859;STR06764;4-Aminonaphthalen-l-ol hydrochloride;4-amino-naphthalen-1-ol hydrochloride;4-aminonaphth-1-ol hydrochloride salt;AKOS005255297;PD148122;SMR000469587;A0366;CS-0204314;FT-0617436;EN300-14794;W-200452;Q27236581;4-Amino-1-naphthol hydrochloride, technical grade, 90%;F2167-0164;Z104442670

Chemical Property of 4-Amino-1-naphthol hydrochloride

Chemical Property:

• Vapor Pressure: 1.54E-06mmHg at 25°C
• Melting Point: 273 ºC (dec.)
• Boiling Point: 386.8°C at 760 mmHg
• Flash Point: 187.8°C
• PSA: 46.25000
• LogP: 3.51080
• Storage Temp.: Inert atmosphere,Room Temperature
• Sensitive.: Hygroscopic
• Solubility.: soluble in Methanol
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 195.0450916
• Heavy Atom Count: 13
• Complexity: 160

Purity/Quality:

99% ^*data from raw suppliers

4-Amino-1-naphthol Hydrochloride >98.0%(HPLC) ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 26-37/39-36

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Nitrogen Compounds -> Naphthylamines
• Canonical SMILES: C1=CC=C2C(=C1)C(=CC=C2O)N.Cl
• Uses: 4-Amino-1-naphthol hydrochloride was used in the synthesis of 2-(3-aminophenol)-6-(4-amino-1-naphthol)-4-chloro-s-triazine. It was used in the synthesis of 4-aminoalkyl-1-naphthol derivatives.

Technology Process of 4-Amino-1-naphthol hydrochloride

There total 1 articles about 4-Amino-1-naphthol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

4-Phenylazo-1-naphthol (3651-02-3) → 4-amino-1-naphthol hydrochloride (5959-56-8)

Guidance literature:

With iron; ammonium chloride; In ethanol; water; for 0.25h; Heating;

DOI:10.1007/s00706-007-0633-2

Reference yield: 95.0%

4-amino-1-naphthol hydrochloride (5959-56-8) + 4-methoxy-phenyl-sulphonyl chloride (98-68-0) → N-(4-hydroxynaphthalen-1-yl)-4-methoxybenzenesulfonamide (301313-43-9)

Guidance literature:

With sodium acetate; In water; at 85 ℃; for 2h;

Reference yield: 92.0%

pentafluorobenzenesulonyl chloride (832-53-1) + 4-amino-1-naphthol hydrochloride (5959-56-8) → 2,3,4,5,6-pentafluoro-N-(4-hydroxynaphthalen-1-yl)benzenesulfonamide

Guidance literature:

With pyridine; magnesium sulfate; In acetonitrile; for 2h;

DOI:10.1002/anie.201506889

upstream raw materials:

4-Phenylazo-1-naphthol

Downstream raw materials:

4--1-naphthol

[1,4]naphthoquinone

2,2'-binaphthoquinone

tert-butyl 4-hydroxynaphthalen-1-ylcarbamate

Refernces