Potassium 4-nitrophenyl sulfate, sulfatase substrate

Base Information

• Chemical Name: Potassium 4-nitrophenyl sulfate, sulfatase substrate
• CAS No.: 6217-68-1
• Molecular Formula: C6H5NO6S^.K
• Molecular Weight: 257.265
• Hs Code.: 29049095
• Mol file: 6217-68-1.mol

Synonyms:Potassium 4-nitrophenyl sulfate, sulfatase substrate

Chemical Property of Potassium 4-nitrophenyl sulfate, sulfatase substrate

Chemical Property:

• Appearance/Colour: Yellowish cyrstalline solid
• Melting Point: 246-250 °C(lit.)
• PSA: 120.63000
• LogP: 2.03780
• Storage Temp.: −20°C
• Solubility.: Water (Slightly)
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 257.94746454
• Heavy Atom Count: 15
• Complexity: 293

Purity/Quality:

98%,99%, ^*data from raw suppliers

Potassium p-Nitrophenyl Sulfate ^*data from reagent suppliers

Safty Information:

• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1[N+](=O)[O-])OS(=O)(=O)O.[K]
• Uses: Potassium p-Nitrophenyl Sulphate (cas# 6217-68-1) is a compound useful in organic synthesis. Potassium 4-nitrophenyl sulfate has been used:as a substrate to measure arylsulfatase activity in cell-free coelomic fluidas a substrate for p-nitrophenyl glycoside-based enzyme assayto inhibit arylsulfataseas an inorganic analog of organic aryl ester sulphate

Technology Process of Potassium 4-nitrophenyl sulfate, sulfatase substrate

There total 3 articles about Potassium 4-nitrophenyl sulfate, sulfatase substrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) → potassium 4-nitrophenylsulfate monoester (6217-68-1)

Guidance literature:

With chlorosulfonic acid; 2,3-Dimethylaniline; In carbon disulfide;

Reference yield:

p-nitrophenyl sulfate (1080-04-2) → potassium 4-nitrophenylsulfate monoester (6217-68-1)

Guidance literature:

With potassium hydroxide;

DOI:10.1039/b513712h

Reference yield:

carbon disulfide (75-15-0,12122-00-8) + 4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) → potassium 4-nitrophenylsulfate monoester (6217-68-1)

Guidance literature:

With 2,3-Dimethylaniline; at 35 ℃; Behandlung des Reaktionsprodukts mit Kalilauge;

DOI:10.1557/JMR.2000.0235

upstream raw materials:

carbon disulfide

4-nitro-phenol

p-nitrophenyl sulfate

Downstream raw materials:

N-hydroxy-N-(4-hydroxyphenyl)acetamide

4-nitro-phenol

Refernces

• 1、 Denehy, Emma,White, Jonathan M.,Williams, Spencer J.. "Ground state structures of sulfate monoesters and sulfamates reveal similar reaction coordinates for sulfuryl and sulfamyl transfer". . p. 314 - 316. Retrieved 2008/02/08.
• 2、 Marzec, Krzysztof,Gniot-Szulzycka, Jadwiga. "The Synthesis of p-Nitrophenyl Sulphate". . p. 371 - 373. Retrieved 2007/10/02.