phenylphosphonofluoridic acid

Base Information

• Chemical Name: phenylphosphonofluoridic acid
• CAS No.: 45778-98-1
• Molecular Formula: C₆H₆FO₂P
• Molecular Weight: 160.085
• Mol file: 45778-98-1.mol

Synonyms:phenylphosphonofluoridic acid

Chemical Property of phenylphosphonofluoridic acid

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of phenylphosphonofluoridic acid

There total 2 articles about phenylphosphonofluoridic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

diphenyl phenylphosphonate (3049-24-9) → phenylphosphonofluoridic acid (45778-98-1)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 0.5h;

DOI:10.1021/acs.orglett.1c01211

Reference yield:

phenyl-phosphonic acid-difluoride (657-39-6) → phenylphosphonofluoridic acid (45778-98-1)

Guidance literature:

With phenylphosphonate; at 20 ℃;

Reference yield:

phenylphosphonofluoridic acid (45778-98-1) → phenyl-phosphonic acid-difluoride (657-39-6)

Guidance literature:

With potassium 2-(difluoro(trifluoromethoxy)methoxy)-2,2-difluoroacetate; In N,N-dimethyl-formamide; at 80 ℃; for 1h; Schlenk technique; Sealed tube; Inert atmosphere;

DOI:10.1002/cjoc.202000662

upstream raw materials:

phenyl-phosphonic acid-difluoride

diphenyl phenylphosphonate

Downstream raw materials:

phenyl-phosphonic acid-difluoride

Refernces