C₁₈H₁₉N₃OS

Base Information

• Chemical Name: C₁₈H₁₉N₃OS
• CAS No.: 1078164-01-8
• Molecular Formula: C₁₈H₁₉N₃OS
• Molecular Weight: 325.434
• Mol file: 1078164-01-8.mol

Synonyms:C₁₈H₁₉N₃OS

Chemical Property of C₁₈H₁₉N₃OS

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₁₈H₁₉N₃OS

There total 1 articles about C₁₈H₁₉N₃OS which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

2,4-dimethylpent-4-en-2-ol (19781-53-4) + C14H12BrN3OS (1078164-00-7) → C18H19N3OS (1078164-01-8)

Guidance literature:

With palladium diacetate; caesium carbonate; tris-(o-tolyl)phosphine; In toluene; at 145 ℃; for 6h; Inert atmosphere;

DOI:10.1021/jo801303v

Reference yield: 64.0%

C18H19N3OS (1078164-01-8) → C17H19N3O (1078164-03-0) + 2-amino-4-(4-methoxyphenyl)-5-(2-methylpropyl)-6-(methylsulfanyl)pyridine-3-carbonitrile (1078164-02-9)

Guidance literature:

With platinum(IV) oxide; hydrogen; In methanol; at 20 ℃; for 72h; under 760.051 Torr;

DOI:10.1021/jo801303v

upstream raw materials:

2,4-dimethylpent-4-en-2-ol

C₁₄H₁₂BrN₃OS

Downstream raw materials:

C₁₇H₁₉N₃O

2-amino-4-(4-methoxyphenyl)-5-(2-methylpropyl)-6-(methylsulfanyl)pyridine-3-carbonitrile

Refernces