Technology Process of 6-tosyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-1-yl trifluoromethanesulfonate
There total 6 articles about 6-tosyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-1-yl trifluoromethanesulfonate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: trifluoroacetic acid / 5 h / 70 °C
2: triethylamine / dichloromethane / 0.5 h / 20 °C
3: palladium(II) trifluoroacetate; silver trifluoroacetate / acetic acid / 36 h / 80 °C / Sealed tube
4: zinc; ammonium chloride / tetrahydrofuran; water / 0.5 h
5: triethylamine / dichloromethane / 0.08 h / 0 °C / Inert atmosphere
With
palladium(II) trifluoroacetate; silver trifluoroacetate; ammonium chloride; triethylamine; trifluoroacetic acid; zinc;
In
tetrahydrofuran; dichloromethane; water; acetic acid;
DOI:10.1021/acs.joc.1c01649
- Guidance literature:
-
Multi-step reaction with 4 steps
1: triethylamine / dichloromethane / 0.5 h / 20 °C
2: palladium(II) trifluoroacetate; silver trifluoroacetate / acetic acid / 36 h / 80 °C / Sealed tube
3: zinc; ammonium chloride / tetrahydrofuran; water / 0.5 h
4: triethylamine / dichloromethane / 0.08 h / 0 °C / Inert atmosphere
With
palladium(II) trifluoroacetate; silver trifluoroacetate; ammonium chloride; triethylamine; zinc;
In
tetrahydrofuran; dichloromethane; water; acetic acid;
DOI:10.1021/acs.joc.1c01649