N(alpha)-Z-L-arginine HCl

Base Information

• Chemical Name: N(alpha)-Z-L-arginine HCl
• CAS No.: 56672-63-0
• Molecular Formula: C14H20N4O4^.HCl
• Molecular Weight: 344.798
• Hs Code.: 29225090
• NSC Number: 164093,88473
• Mol file: 56672-63-0.mol

Synonyms:N(alpha)-Z-L-arginine HCl;Z-arg-oh.hci;Cbz-Arg-OH.HCl;Z-L-Arg-OH.HCl;SCHEMBL333888;(R)-2-(benzyloxycarbonylamino)-5-guanidinopentanoic acid hydrochloride;(S)-2-(benzyloxycarbonylamino)-5-guanidinopentanoic acid hydrochloride;NSC88473;NSC-88473;NSC164093;NSC-164093;Z-Arg-OH inverted exclamation mark currencyHCl

Chemical Property of N(alpha)-Z-L-arginine HCl

Chemical Property:

• Refractive Index: 1.594
• Boiling Point: 574 °C at 760 mmHg
• Flash Point: 301 °C
• PSA: 137.53000
• Density: 1.33g/cm3
• LogP: 3.01310
• Storage Temp.: Store at RT.
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 9
• Exact Mass: 344.1251329
• Heavy Atom Count: 23
• Complexity: 390

Purity/Quality:

99% ^*data from raw suppliers

N(α)-Z-L-ArginineHydrochloride ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)COC(=O)NC(CCCN=C(N)N)C(=O)O.Cl

Technology Process of N(alpha)-Z-L-arginine HCl

There total 3 articles about N(alpha)-Z-L-arginine HCl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-O-(N-Cbz-L-arginyl)-rac-glycerol hydrochloride → Z-Arg-OH hydrochloride (56672-63-0) + glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0)

Guidance literature:

In water; Further Variations:; pH-values; Temperatures; Kinetics;

DOI:10.1039/b203896j

Reference yield:

n-Dodecylamine (124-22-1) + Nα-benzyloxycarbonyl-arginine methyl ester hydrochloride (5134-44-1) → Nα-benzyloxycarbonyl-arginine N-dodecylamide hydrochloride (259141-27-0) + Z-Arg-OH hydrochloride (56672-63-0)

Guidance literature:

With papain; In acetonitrile; for 24h; Enzymatic reaction;

Reference yield:

1-dodecyl alcohol (112-53-8) + Nα-benzyloxycarbonyl-arginine methyl ester hydrochloride (5134-44-1) → Nα-benzyloxycarbonyl-arginine O-dodecyl ester hydrochloride + Z-Arg-OH hydrochloride (56672-63-0)

Guidance literature:

With papain; In acetonitrile; for 96h; Enzymatic reaction;

upstream raw materials:

n-Dodecylamine

Nα-benzyloxycarbonyl-arginine methyl ester hydrochloride

1-dodecyl alcohol

Downstream raw materials:

N-α-Benzyloxycarbonyl-L-arginine 4-Methylcoumaryl-7-amide Hydrochloride

Z-L-Arg-pNA*HCl

Refernces

• 1、 Perez,Pinazo,Vinardell,Clapes,Angelet,Infante. "Synthesis and biological properties of dicationic arginine-diglycerides". . p. 1221 - 1227. Retrieved 2007/10/03.