2,5-Dimethyl-4-ethylthiazole

Base Information

• Chemical Name: 2,5-Dimethyl-4-ethylthiazole
• CAS No.: 32272-57-4
• Molecular Formula: C₇H₁₁NS
• Molecular Weight: 141.237
• Hs Code.: 2934100090
• UNII: N9ZS090JBQ
• DSSTox Substance ID: DTXSID10186021
• Nikkaji Number: J108.858K
• Wikidata: Q27284751
• Metabolomics Workbench ID: 48808
• Mol file: 32272-57-4.mol

Synonyms:2,5-DIMETHYL-4-ETHYLTHIAZOLE;4-Ethyl-2,5-dimethylthiazole;32272-57-4;4-Ethyl-2,5-dimethyl-1,3-thiazole;Thiazole, 4-ethyl-2,5-dimethyl-;UNII-N9ZS090JBQ;N9ZS090JBQ;4-Ethyl-2,5-dimethyl-Thiazole;SCHEMBL6760698;DTXSID10186021;AKOS006239019;4-Ethyl-2,5-dimethyl-1,3-thiazole #;Q27284751

Chemical Property of 2,5-Dimethyl-4-ethylthiazole

Chemical Property:

• Vapor Pressure: 0.484mmHg at 25°C
• Boiling Point: 199.4°C at 760 mmHg
• Flash Point: 71.9°C
• PSA: 41.13000
• Density: 1.027g/cm³
• LogP: 2.32230
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 141.06122053
• Heavy Atom Count: 9
• Complexity: 94.9

Purity/Quality:

99%min ^*data from raw suppliers

2,5-DIMETHYL-4-ETHYLTHIAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1=C(SC(=N1)C)C

Technology Process of 2,5-Dimethyl-4-ethylthiazole

There total 13 articles about 2,5-Dimethyl-4-ethylthiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-ethyl-2,5-dimethyl-4,5-dihydro-thiazol-4-ol (32272-45-0) → 2,5-Dimethyl-4-ethylthiazol (32272-57-4)

Guidance literature:

With zinc(II) chloride; In methanol; for 4h; Heating;

Reference yield:

3-acetamidopentan-2-one (30408-57-2) → 2,5-Dimethyl-4-ethylthiazol (32272-57-4)

Guidance literature:

With tiolacetic acid; zinc(II) chloride; In 1,4-dioxane;

DOI:10.1007/BF00928096

Reference yield:

2-bromopentan-3-one (815-52-1) → 2,5-Dimethyl-4-ethylthiazol (32272-57-4)

Guidance literature:

Multi-step reaction with 2 steps

1: acetone / 1.5 h / Heating

2: ZnCl₂ / methanol / 4 h / Heating

With zinc(II) chloride; In methanol; acetone;

upstream raw materials:

acetamide

2-bromopentan-3-one

2-mercapto-pentan-3-one

4-ethyl-2,5-dimethyl-2,5-dihydro-thiazole