HU-308

Base Information

• Chemical Name: HU-308
• CAS No.: 1220887-84-2
• Molecular Formula: C₂₇H₄₂O₃
• Molecular Weight: 414.629
• DSSTox Substance ID: DTXSID901010005
• Wikipedia: HU-308
• Wikidata: Q550052
• NCI Thesaurus Code: C184881
• Pharos Ligand ID: UHJ2M1TR3VRN
• ChEMBL ID: CHEMBL3613118
• Mol file: 1220887-84-2.mol

Synonyms:bicyclo(3.1.1)hept-2-ene-2-methanol, 4-(4-(1,1-dimethylheptyl)-2,6-dimethoxyphenyl)-6,6-dimethyl-, (1R,4S,5R)-;HU 308;HU 433;HU-308;HU308

Chemical Property of HU-308

Chemical Property:

• Boiling Point: 508.7±50.0 °C(Predicted)
• Density: 0.999±0.06 g/cm3(Predicted)
• XLogP3: 7.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 10
• Exact Mass: 414.31339520
• Heavy Atom Count: 30
• Complexity: 579

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCCCCCC(C)(C)C1=CC(=C(C(=C1)OC)C2C=C(C3CC2C3(C)C)CO)OC
• Isomeric SMILES: CCCCCCC(C)(C)C1=CC(=C(C(=C1)OC)[C@@H]2C=C([C@@H]3C[C@H]2C3(C)C)CO)OC
• Uses: HU 433 is a a promising therapeutic target for various forms of tissue injury and inflammatory diseases. It is an enantiomer of HU 308, a cannabinoid CB2 receptor.

Technology Process of HU-308

There total 1 articles about HU-308 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(3-myrtenyl-pivalate)-5-dimethylheptyl dimethylresorcinol (1220887-85-3) → HU-433 (1220887-84-2,256934-39-1)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 2h; Reflux;

upstream raw materials:

2-(3-myrtenyl-pivalate)-5-dimethylheptyl dimethylresorcinol

Refernces