C₁₄H₁₂F₃NO₃S

Base Information

• Chemical Name: C₁₄H₁₂F₃NO₃S
• CAS No.: 1048009-47-7
• Molecular Formula: C₁₄H₁₂F₃NO₃S
• Molecular Weight: 331.315
• Mol file: 1048009-47-7.mol

Synonyms:C₁₄H₁₂F₃NO₃S

Chemical Property of C₁₄H₁₂F₃NO₃S

Chemical Property:

Purity/Quality:

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Technology Process of C₁₄H₁₂F₃NO₃S

There total 1 articles about C₁₄H₁₂F₃NO₃S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

N,N-phenylbistrifluoromethane-sulfonimide (37595-74-7) + 4-cyano-4-phenylcyclohexanone (25115-74-6) → C14H12F3NO3S (1048009-47-7)

Guidance literature:

With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1021/acs.orglett.9b00765

Reference yield: 68.0%

C14H12F3NO3S (1048009-47-7) + carbon monoxide (201230-82-2) → C14H13NO (1048009-61-5)

Guidance literature:

With N,N,N,N,-tetramethylethylenediamine; α,α′-bis(2-pyridyl(tert-butyl)phosphino)-o-xylene; hydrogen; palladium diacetate; In toluene; at 60 ℃; for 16h; under 3750.38 Torr; Autoclave;

DOI:10.1021/acs.orglett.9b00765

upstream raw materials:

N,N-phenylbistrifluoromethane-sulfonimide

4-cyano-4-phenylcyclohexanone

Downstream raw materials:

C₁₄H₁₃NO

Refernces