methyl 4-(allyloxy)-3,5-dimethoxybenzoate

Base Information

• Chemical Name: methyl 4-(allyloxy)-3,5-dimethoxybenzoate
• CAS No.: 1147-85-9
• Molecular Formula: C₁₃H₁₆O₅
• Molecular Weight: 252.267
• Mol file: 1147-85-9.mol

Synonyms:methyl 4-(allyloxy)-3,5-dimethoxybenzoate

Chemical Property of methyl 4-(allyloxy)-3,5-dimethoxybenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of methyl 4-(allyloxy)-3,5-dimethoxybenzoate

There total 4 articles about methyl 4-(allyloxy)-3,5-dimethoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methyl 3,5-dihydroxy-4-allyloxy benzoate (21022-88-8) + methyl iodide (74-88-4) → methyl 4-(allyloxy)-3,5-dimethoxybenzoate (1147-85-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 5h;

DOI:10.1080/00397919608004560

Reference yield:

methyl syringate (884-35-5) + allyl bromide (106-95-6) → methyl 4-(allyloxy)-3,5-dimethoxybenzoate (1147-85-9)

Guidance literature:

With potassium carbonate; acetone;

Reference yield:

3,5-dimethoxy-4-hydroxybenzoic acid (530-57-4) → methyl 4-(allyloxy)-3,5-dimethoxybenzoate (1147-85-9)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogen chloride

2: potassium carbonate; acetone

With hydrogenchloride; potassium carbonate; acetone;

upstream raw materials:

methyl syringate

allyl bromide

methyl 3,5-dihydroxy-4-allyloxy benzoate

methyl iodide

Downstream raw materials:

5-allyl-2-benzoyloxy-1,3-dimethoxy-benzene

methyl syringate

4-allyl-2,6-dimethoxyphenol

Refernces

• 1、 Zhu, Jieping,Chastanet, Jacqueline,Beugelmans, Rene. "Selective hydroxy group protection of gallic acid". . p. 2479 - 2486. Retrieved 2007/10/03.