1-(p-Methoxybenzoyl)aziridine

Base Information

• Chemical Name: 1-(p-Methoxybenzoyl)aziridine
• CAS No.: 15269-50-8
• Molecular Formula: C10H11 N O2
• Molecular Weight: 177.203
• Hs Code.: 2933990090
• NSC Number: 96325
• UNII: 1QLF66ZU3Z
• DSSTox Substance ID: DTXSID60165104
• Nikkaji Number: J54.707G
• Wikidata: Q83034252
• Mol file: 15269-50-8.mol

Synonyms:1-(p-Methoxybenzoyl)aziridine;Aziridine, 1-p-anisoyl-;15269-50-8;N-(4-Methoxybenzoyl)aziridine;1-(4-Methoxybenzoyl)aziridine;aziridin-1-yl-(4-methoxyphenyl)methanone;AZIRIDINE, 1-(p-METHOXYBENZOYL)-;Aziridine, 1-(4-methoxybenzoyl)-;NSC 96325;Aziridine, 1-p-anixoyl- (7CI,8CI);BRN 1343666;1QLF66ZU3Z;AI3-50739;NSC-96325;5-20-01-00057 (Beilstein Handbook Reference);Methanone, 1-aziridinyl(4-methoxyphenyl)-;NSC96325;Aziridine, 1-p-anixoyl-;UNII-1QLF66ZU3Z;WLN: T3NTJ AVR DO1;DTXSID60165104;LS-23272;1-AZIRIDINYL(4-METHOXYPHENYL)METHANONE

Chemical Property of 1-(p-Methoxybenzoyl)aziridine

Chemical Property:

• Vapor Pressure: 0.000162mmHg at 25°C
• Boiling Point: 330.8°C at 760 mmHg
• Flash Point: 153.9°C
• PSA: 29.31000
• Density: 1.219g/cm³
• LogP: 1.08890
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 177.078978594
• Heavy Atom Count: 13
• Complexity: 193

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C(=O)N2CC2

Technology Process of 1-(p-Methoxybenzoyl)aziridine

There total 2 articles about 1-(p-Methoxybenzoyl)aziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

ethyleneimine (151-56-4,9002-98-6) + 4-methoxy-benzoyl chloride (100-07-2) → 1-(4-methoxy-benzoyl)-aziridine (15269-50-8)

Guidance literature:

With sodium hydroxide; In benzene; at 0 ℃; for 0.5h;

DOI:10.1021/jo00381a019

Reference yield:

→ 1-(4-methoxy-benzoyl)-aziridine (15269-50-8)

Guidance literature:

4-Methoxy-benzoylchlorid, Ethylenimin, Methylenchlorid, wss. NaOH <-10grad => 0grad>;

DOI:10.1021/jm00333a036

Reference yield:

1-(4-methoxy-benzoyl)-aziridine (15269-50-8) → ethyleneimine (151-56-4,9002-98-6) + sodium anisate (536-45-8)

Guidance literature:

With sodium hydroxide; In acetonitrile; at 25 ℃; Rate constant; var. pH (from 13 to neutral);

DOI:10.1021/jo00381a019

upstream raw materials:

ethyleneimine

4-methoxy-benzoyl chloride

Downstream raw materials:

4-Methoxy-N-(2-methoxy-ethyl)-benzamide

ethyleneimine

sodium anisate

N-(2-hydroxyethyl)-p-methoxybenzamide

Refernces