S-(2-Aminoethyl)-L-cysteine hydrochloride

Base Information

• Chemical Name: S-(2-Aminoethyl)-L-cysteine hydrochloride
• CAS No.: 4099-35-8
• Molecular Formula: C5H12 N2 O2 S . Cl H
• Molecular Weight: 200.689
• Hs Code.: 2930909090
• European Community (EC) Number: 243-948-2
• UNII: WPH5RH5BID
• DSSTox Substance ID: DTXSID50942860
• Mol file: 4099-35-8.mol

Synonyms:4099-35-8;S-(2-Aminoethyl)-L-cysteine hydrochloride;Thialysine hydrochloride;H-Cys(aminoethyl)-OH HCl;20662-32-2;Thialysine HCl;S-(2-Aminoethyl)-L-cysteine HCl;S-(2-Aminoethyl)-l-cysteine, HCl;Thialysine (hydrochloride);LJ 226;NSC 186915;NSC-186915;WPH5RH5BID;(R)-2-Amino-3-((2-aminoethyl)thio)propanoic acid hydrochloride;(2R)-2-amino-3-(2-aminoethylsulfanyl)propanoic acid;hydrochloride;S-(2-Aminoethyl)cysteine hydrochloride;(2R)-2-amino-3-[(2-aminoethyl)sulfanyl]propanoic acid hydrochloride;EINECS 243-948-2;S-2-Aminoethyl-L-cysteine hydrochloride;H-Cys(Et-NH2)-OH.HCl;SCHEMBL5494298;DTXSID50942860;MFCD00036385;AKOS015894672;FD21310;L-4-Thialysine HCl;L-Thiosine HCl;S-(aminoethyl)-L-cysteine hydrochloride;AS-49033;HY-122526;S-(2-Aminoethyl)-l-cysteine, hydrochloride;CS-0086292;A-5450;S-(2-Aminoethyl)cysteine--hydrogen chloride (1/1);S-(2-Aminoethyl)-L-cysteine hydrochloride, >=98% (TLC);(R)-2-amino-3-(2-aminoethylthio)propanoic acid hydrochloride;L-CYSTEINE, S-(2-AMINOETHYL)-, HYDROCHLORIDE (1:1)

Chemical Property of S-(2-Aminoethyl)-L-cysteine hydrochloride

Chemical Property:

• Vapor Pressure: 9.63E-06mmHg at 25°C
• Melting Point: 195 °C (decomp)
• Boiling Point: 347.2°C at 760 mmHg
• Flash Point: 163.8°C
• PSA: 114.64000
• Density: 1.289g/cm3
• LogP: 1.29280
• Storage Temp.: 2-8°C
• Solubility.: Methanol (Slightly), Water (Slightly, Sonicated)
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 200.0386265
• Heavy Atom Count: 11
• Complexity: 110

Purity/Quality:

99% ^*data from raw suppliers

S-(2-Aminoethyl)-L-cysteine hydrochloride ≥98% (TLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CSCC(C(=O)O)N)N.Cl
• Isomeric SMILES: C(CSC[C@@H](C(=O)O)N)N.Cl
• Uses: S-(2-Aminoethyl)-l-cysteine, HCl

Technology Process of S-(2-Aminoethyl)-L-cysteine hydrochloride

There total 2 articles about S-(2-Aminoethyl)-L-cysteine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2-mercaptoethylamine hydrochloride (156-57-0) + (S)-3-amino-2-oxetanone trifluoroacetic acid salt (112839-94-8) → S-(aminoethyl)-L-cysteine hydrochloride (4099-35-8)

Guidance literature:

In water; for 0.583333h; pH = 5.0-5.5;

DOI:10.1021/ja00215a038

Reference yield:

S-(2-benzyloxycarbonylamino-ethyl)-L-cysteine (41889-04-7) → S-(aminoethyl)-L-cysteine hydrochloride (4099-35-8)

Guidance literature:

With hydrogen bromide; acetic acid;

Reference yield:

S-(aminoethyl)-L-cysteine hydrochloride (4099-35-8) + Cyclohexyl isocyanate (3173-53-3) → (R)-2-Amino-3-[2-(3-cyclohexyl-ureido)-ethylsulfanyl]-propionic acid

Guidance literature:

S-(aminoethyl)-L-cysteine hydrochloride; In water; at 90 ℃;

Cyclohexyl isocyanate; With potassium hydroxide; In water; at 0 ℃; for 4.5h;

With hydrogenchloride; hydrogen sulfide; In water;

DOI:10.1007/BF02218869

upstream raw materials:

S-(2-benzyloxycarbonylamino-ethyl)-L-cysteine

2-mercaptoethylamine hydrochloride

(S)-3-amino-2-oxetanone trifluoroacetic acid salt