2-[1-(Diaminomethylidenehydrazinylidene)propan-2-ylideneamino]guanidine;dihydrochloride

Base Information

• Chemical Name: 2-[1-(Diaminomethylidenehydrazinylidene)propan-2-ylideneamino]guanidine;dihydrochloride
• CAS No.: 7059-23-6
• Molecular Formula: C5H12ClN8-
• Molecular Weight: 257.12426
• DSSTox Substance ID: DTXSID901036405
• NCI Thesaurus Code: C91409
• Mol file: 7059-23-6.mol

Synonyms:MITOGUAZONE DIHYDROCHLORIDE;DTXSID901036405

Chemical Property of 2-[1-(Diaminomethylidenehydrazinylidene)propan-2-ylideneamino]guanidine;dihydrochloride

Chemical Property:

• Melting Point: 256 °C (decomp)
• Boiling Point: 436.6oC at 760 mmHg
• Flash Point: 217.8oC
• PSA: 148.52000
• LogP: 1.49810
• Storage Temp.: -20°
• Solubility.: Soluble in Water (greater than 25 mg/ml).
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 256.0718479
• Heavy Atom Count: 15
• Complexity: 264

Purity/Quality:

99% ^*data from raw suppliers

MITOGUAZONE DIHYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=NN=C(N)N)C=NN=C(N)N.Cl.Cl
• Description: Mitoguazone (7059-23-6) is a potent and reversible inhibitor of S-adenosylmethionine decarboxylase (SAMD or AdoMetDC).1,2?SAMD is a component of the polyamine-biosynthetic pathway, thus inhibition may lead to changes in polyamine metabolism.3?Mitoguazone has also been shown to inhibit diamine oxidase and induce spermidine/spermine N-acetyltransferase.4,5 Mitoguazone has been looked at as a potential anti-cancer treatment because of its ability to inhibit polyamine synthesis.6