3-(2'-benzoyl-4'-chlorophenyl)-4-imidazolidinone hydrochloride

Base Information

• Chemical Name: 3-(2'-benzoyl-4'-chlorophenyl)-4-imidazolidinone hydrochloride
• CAS No.: 2319-27-9
• Molecular Formula: C₁₆H₁₃ClN₂O₂*ClH
• Molecular Weight: 337.205
• Mol file: 2319-27-9.mol

Synonyms:3-(2'-benzoyl-4'-chlorophenyl)-4-imidazolidinone hydrochloride

Chemical Property of 3-(2'-benzoyl-4'-chlorophenyl)-4-imidazolidinone hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 3-(2'-benzoyl-4'-chlorophenyl)-4-imidazolidinone hydrochloride

There total 2 articles about 3-(2'-benzoyl-4'-chlorophenyl)-4-imidazolidinone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

N,N'-methylenebis<3-(2-benzoyl-4'-chloro)phenyl>-4-imidazolidinone (2147-78-6) → 3-(2'-benzoyl-4'-chlorophenyl)-4-imidazolidinone hydrochloride (2319-27-9)

Guidance literature:

With hydrogenchloride; In ethanol; chloroform; for 0.25h; Ambient temperature;

DOI:10.1002/jhet.5570180523

Reference yield:

5-chloro-2-(chloroacetylamino)benzophenone (4016-85-7) → 3-(2'-benzoyl-4'-chlorophenyl)-4-imidazolidinone hydrochloride (2319-27-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / aq. ethanol / 60 deg C, 1 h, then reflux, 1.5 h

2: 95 percent / conc. hydrochloric acid / CHCl₃; aq. ethanol / 0.25 h / Ambient temperature

With hydrogenchloride; In ethanol; chloroform;

DOI:10.1002/jhet.5570180523

Reference yield: 100.0%

3-(2'-benzoyl-4'-chlorophenyl)-4-imidazolidinone hydrochloride (2319-27-9) → desmethyldiazepam (1088-11-5)

Guidance literature:

With ammonium hydroxide; In ethanol; Heating;

DOI:10.1002/jhet.5570180523

upstream raw materials:

N,N'-methylenebis<3-(2-benzoyl-4'-chloro)phenyl>-4-imidazolidinone

5-chloro-2-(chloroacetylamino)benzophenone

Downstream raw materials:

desmethyldiazepam

Refernces