Technology Process of 9H-xanthene-9-carboxylic acid benzylamide
There total 1 articles about 9H-xanthene-9-carboxylic acid benzylamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
xanthene-9-carboxylic acid;
With
N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline;
In
dichloromethane;
for 0.5h;
Inert atmosphere;
benzylamine;
In
dichloromethane;
at 20 ℃;
Inert atmosphere;
DOI:10.1021/jm301706j
- Guidance literature:
-
With
aluminum (III) chloride; lithium aluminium tetrahydride;
In
tetrahydrofuran;
at 0 - 50 ℃;
for 5h;
Inert atmosphere;
DOI:10.1021/jm301706j
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: lithium aluminium tetrahydride / aluminum (III) chloride / tetrahydrofuran / 0.17 h / 0 °C
1.2: 5 h / 0 - 50 °C
1.3: 20 °C
2.1: hydrogen / palladium 10% on activated carbon / ethanol / 760.05 Torr
3.1: 6-chloro-3-((dimethylamino)(dimethyliminio)methyl)-1H-benzo[d][1,2,3]triazol-3-ium-1-olatehexafluorophosphate(V); N-ethyl-N,N-diisopropylamine / dichloromethane; acetonitrile / 0.25 h / 0 °C
3.2: 15 h / 0 - 20 °C
4.1: piperidine / dichloromethane / 1 h / 20 °C
With
piperidine; lithium aluminium tetrahydride; 6-chloro-3-((dimethylamino)(dimethyliminio)methyl)-1H-benzo[d][1,2,3]triazol-3-ium-1-olatehexafluorophosphate(V); hydrogen; N-ethyl-N,N-diisopropylamine;
aluminum (III) chloride; palladium 10% on activated carbon;
In
tetrahydrofuran; ethanol; dichloromethane; acetonitrile;
