3,17-Divinyl-1,10,19,22,23,24-hexahydro-2,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropionic acid

Base Information

• Chemical Name: 3,17-Divinyl-1,10,19,22,23,24-hexahydro-2,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropionic acid
• CAS No.: 35991-50-5
• Molecular Formula: C33H36N4O6
• Molecular Weight: 584.672
• Mol file: 35991-50-5.mol

Synonyms:3,3'-(2,7,13,18-Tetramethyl-1,19-dioxo-3,17-divinyl-10,19,21,22,23,24-hexahydro-1H-bilin-8,12-diyl)-di-propionsaeure;bilirubin XIIIα;3,3'-(2,7,13,18-tetramethyl-1,19-dioxo-3,17-divinyl-10,19,21,22,23,24-hexahydro-1H-bilin-8,12-diyl)-di-propionic acid;3,3'-(2,7,13,18-tetramethyl-1,19-dioxo-3,17-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-diyl)-bis-propionic acid;

Chemical Property of 3,17-Divinyl-1,10,19,22,23,24-hexahydro-2,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropionic acid

Chemical Property:

• PSA: 164.38000
• LogP: 5.18880

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,17-Divinyl-1,10,19,22,23,24-hexahydro-2,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropionic acid

There total 2 articles about 3,17-Divinyl-1,10,19,22,23,24-hexahydro-2,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.0%

bilirubin (635-65-4,114-24-9) → 4Z,15Z-bilirubin (35991-50-5) + bilirubin (36284-06-7)

Guidance literature:

In hydrogenchloride; dimethyl sulfoxide;

Reference yield:

18-Devinyl-18-(1-carboxymethylthio)ethyl-bilirubin-IXα (80575-27-5) → 4Z,15Z-bilirubin (35991-50-5) + 2,18-Bis-devinyl-2,18-bis-(1-carboxymethylthio)ethyl-bilirubin-IIIα (80575-28-6) + bilirubin (635-65-4,114-24-9)

Guidance literature:

With hydrogenchloride; In dimethyl sulfoxide; for 0.0166667h; Product distribution; Ambient temperature;

DOI:10.1002/jhet.5570210415

Reference yield: 61.0%

methanol (67-56-1) + 4Z,15Z-bilirubin (35991-50-5) → 2,7-dimethyl-3-vinyl-8-carboxyethyl-9-methoxymethylpyrromethenone + Sodium; 4-{3-(2-carboxy-ethyl)-4-methyl-5-[4-methyl-5-oxo-3-vinyl-1,5-dihydro-pyrrol-(2Z)-ylidenemethyl]-1H-pyrrol-2-ylazo}-benzenesulfonate

Guidance literature:

With sodium hydroxide; 4-sulfobenzenediazonium; In chloroform; for 0.25h; Ambient temperature;

DOI:10.1016/S0040-4020(01)88702-0

upstream raw materials:

18-Devinyl-18-(1-carboxymethylthio)ethyl-bilirubin-IXα

bilirubin

Refernces

• 1、 Defoin-Straatmann, Rosalie,Defoin, Albert,Kuhn, Hans Joachim,Schaffner, Kurt. "Chromatographic Separation and Spectroscopic Characterization of the Bilirubin Isomers IIIα, IXα, XIIIα, and Their Dimethyl Esters". . p. 1759 - 1765. Retrieved 2007/10/02.