butyl-carbamic acid 1-benzyl-1H-[1,2,3]triazol-4-ylmethyl ester

Base Information

• Chemical Name: butyl-carbamic acid 1-benzyl-1H-[1,2,3]triazol-4-ylmethyl ester
• CAS No.: 1313994-71-6
• Molecular Formula: C₁₅H₂₀N₄O₂
• Molecular Weight: 288.349
• Mol file: 1313994-71-6.mol

Synonyms:butyl-carbamic acid 1-benzyl-1H-[1,2,3]triazol-4-ylmethyl ester

Chemical Property of butyl-carbamic acid 1-benzyl-1H-[1,2,3]triazol-4-ylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of butyl-carbamic acid 1-benzyl-1H-[1,2,3]triazol-4-ylmethyl ester

There total 2 articles about butyl-carbamic acid 1-benzyl-1H-[1,2,3]triazol-4-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

benzyl azide (622-79-7) + butylcarbamic acid prop-2-ynyl ester (76114-73-3) → butyl-carbamic acid 1-benzyl-1H-[1,2,3]triazol-4-ylmethyl ester (1313994-71-6)

Guidance literature:

With (3-hydroxy-3-phenyl-2-propenedithioate S,S′)bis(triphenylphosphine-P)copper(I); In chloroform; at 60 ℃; for 5h; Reagent/catalyst;

DOI:10.1139/cjc-2012-0325

Reference yield:

benzyl bromide (100-39-0) → butyl-carbamic acid 1-benzyl-1H-[1,2,3]triazol-4-ylmethyl ester (1313994-71-6)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium azide / N,N-dimethyl-formamide / 12 h / 30 °C / Inert atmosphere

2: iron-copper nanoparticles powder / methanol / 12 h / 20 °C

With sodium azide; In methanol; N,N-dimethyl-formamide;

DOI:10.2174/157017812800167457

upstream raw materials:

benzyl azide

butylcarbamic acid prop-2-ynyl ester

benzyl bromide

Refernces

• 1、 Ramírez-Palma, María Teresa,Segura-Arzate, Jesús,López-Téllez, Gustavo,Cuevas-Ya?ez, Erick. "Ligand Synthesis Catalyst and Complex Metal Ion: Multicomponent Synthesis of 1,3-Bis(4-phenyl-[1,2,3]triazol-1-yl)-propan-2-ol Copper(I) Complex and Application in Copper-Catalyzed Alkyne-Azide Cycloaddition". . . Retrieved 2016/06/09.
• 2、 Garcia, Marco A.,Rios, Zita G.,Gonzalez, Jaime,Perez, Victor M.,Lara, Nancy,Fuentes, Aydee,Gonzalez, Carlos,Corona, David,Cuevas-Yanez, Erick. "The use of glucose as alternative reducing agent in copper-catalyzed alkyne-azide cycloaddition". experimental part. p. 701 - 706. Retrieved 2012/06/01.