Dimethoxanate hydrochloride

Base Information

• Chemical Name: Dimethoxanate hydrochloride
• CAS No.: 518-63-8
• Molecular Formula: C19H23ClN2O3S
• Molecular Weight: 394.922
• European Community (EC) Number: 208-255-1
• NSC Number: 169183
• UNII: N5I6SR31GJ
• DSSTox Substance ID: DTXSID30199734
• Wikidata: Q27284577
• NCI Thesaurus Code: C76473
• ChEMBL ID: CHEMBL2106376
• Mol file: 518-63-8.mol

Synonyms:DIMETHOXANATE HYDROCHLORIDE;518-63-8;Tussizid;Perlatos;Catrane;Cothera;Dimethoxanate HCl;Dimetoxanate hydrochloride;Dimethoxanate monohydrochloride;Cotrane;Atuss;EINECS 208-255-1;UNII-N5I6SR31GJ;NSC 169183;NSC-169183;N5I6SR31GJ;2-[2-(dimethylamino)ethoxy]ethyl phenothiazine-10-carboxylate;hydrochloride;10H-Phenothiazine-10-carboxylic acid, 2-(2-(dimethylamino)ethoxy)ethyl ester, monohydrochloride;Ethanol, 2-(2-(dimethylamino)ethoxy)-, phenothiazine-10-carboxylate (ester), hydrochloride;Phenothiazine-10-carboxylic acid 2-(2-(dimethylamino)ethoxy)ethyl ester hydrochloride;2-(2-Dimethylaminoethoxy)ethyl phenothiazine-10-carboxylate hydrochloride;beta-Dimethylaminoethoxyethyl phenothiazine-10-carboxylate hydrochloride;2-(2-(Dimethylamino)ethoxy)ethyl phenothiazine-10-carboxylate hydrochloride;2-[2-(Dimethylamino)ethoxy]ethyl phenothiazine-10-carboxylate hydrochloride;Phenothiazine-10-carboxylic acid, 2-(2-(dimethylamino)ethoxy)ethyl ester, monohydrochloride;Phenothiazine-10-carboxylic acid 2-[2-(dimethylamino)ethoxy]ethyl ester hydrochloride;Atuss (TN);Dimethoxanatehydrochloride;C19H22N2O3S.ClH;SCHEMBL4418926;CHEMBL2106376;DTXSID30199734;NSC169183;2-[2-(dimethylamino)ethoxy]ethyl phenothiazine-10-carboxylate,hydrochloride;DIMETHOXANATE HYDROCHLORIDE [MART.];DIMETHOXANATE HYDROCHLORIDE [WHO-DD];LS-105328;D07850;WLN: T C666 BN ISJ BVO2O2N1&1 &GH;Q27284577;1OH-Phenothiazine-10-carboxylic acid, monohydrochloride;Ethanol, phenothiazine-10-carboxylate (ester), hydrochloride;2-[(Dimethylamino)ethoxy]ethyl 10-phenothiazinecarboxylate hydrochloride;Phenothiazine, beta-dimethylaminoethoxyethyl-10-carboxylate-, hydrochloride;.beta.-[(Dimethylamino)ethoxy]ethyl phenothiazine-10-carboxylate hydrochloride

Chemical Property of Dimethoxanate hydrochloride

Chemical Property:

• Vapor Pressure: 6.7E-10mmHg at 25°C
• Melting Point: 161-163 °C (decomp)
• Boiling Point: 494 °C at 760 mmHg
• Flash Point: 252.6 °C
• PSA: 67.31000
• LogP: 4.87110
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 7
• Exact Mass: 394.1117915
• Heavy Atom Count: 26
• Complexity: 413

Purity/Quality:

98%,99%, ^*data from raw suppliers

Dimethoxanate hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CCOCCOC(=O)N1C2=CC=CC=C2SC3=CC=CC=C31.Cl
• Therapeutic Function: Antitussive

Technology Process of Dimethoxanate hydrochloride

There total 1 articles about Dimethoxanate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-O-Dimethylaminoethyl-ethylenglykol (1704-62-7) + 10H-phenothiazine-10-carbonyl chloride (18956-87-1) → dimethoxanate hydrochloride (518-63-8)

Guidance literature:

anschliessendes Behandeln mit HCl in Aether;

upstream raw materials:

1-O-Dimethylaminoethyl-ethylenglykol

10H-phenothiazine-10-carbonyl chloride