1-(8-Hydroxyquinolin-5-yl)ethanone

Base Information Edit

Chemical Name:1-(8-Hydroxyquinolin-5-yl)ethanone
CAS No.:2598-31-4
Molecular Formula:C11H9 N O2
Molecular Weight:187.198
Hs Code.:2933499090
NSC Number:68447,40901
UNII:2KE2DMA89S
DSSTox Substance ID:DTXSID90180643
Nikkaji Number:J342.997K
Wikidata:Q27254868
ChEMBL ID:CHEMBL3251395
Mol file:2598-31-4.mol

Synonyms:2598-31-4;1-(8-hydroxyquinolin-5-yl)ethanone;Quinacetol;1-(8-Hydroxy-5-quinolinyl)ethanone;5-Acetyloxine;5-Acetyl-8-hydroxyquinoline;Quinacetol sulfate;Quinacetol sulfate [ISO];Quinacetol free base;Ethanone, 1-(8-hydroxy-5-quinolinyl)-;1-(8-HYDROXYQUINOLIN-5-YL)ETHAN-1-ONE;8-Hydroxy-5-quinolyl methyl ketone;UNII-2KE2DMA89S;BRN 0135793;2KE2DMA89S;2598-31-4 (free base);Ketone, 8-hydroxy-5-quinolyl methyl;NSC-40901;NSC-68447;5-21-12-00460 (Beilstein Handbook Reference);NSC40901;NSC 40901;NSC 68447;SCHEMBL163474;CHEMBL3251395;DTXSID90180643;1-(8-hydroxy-5-quinolyl)ethanone;NSC68447;MFCD00086061;AKOS015897225;PB12081;1-(8-hydroxy(quinolin-5-yl))ethanone;AS-50390;LS-87247;CS-0052858;FT-0674263;P10073;EN300-1276904;Ethanone, 1-(8-hydroxy-5-quinolinyl)- (9CI);A853360;Q550540;Q27254868

Suppliers and Price of 1-(8-Hydroxyquinolin-5-yl)ethanone

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Quinacetol
1g
$ 1190.00

SynQuest Laboratories
1-(8-Hydroxyquinolin-5-yl)ethan-1-one 97.0%
5 g
$ 630.00

SynQuest Laboratories
1-(8-Hydroxyquinolin-5-yl)ethan-1-one 97.0%
250 mg
$ 160.00

SynQuest Laboratories
1-(8-Hydroxyquinolin-5-yl)ethan-1-one 97.0%
1 g
$ 400.00

Matrix Scientific
1-(8-Hydroxyquinolin-5-yl)ethanone 97.0%
1g
$ 281.00

Crysdot
1-(8-Hydroxyquinolin-5-yl)ethanone 95+%
5g
$ 640.00

Chemenu
1-(8-Hydroxyquinolin-5-yl)ethanone 95%
5g
$ 505.00

Apolloscientific
1-(8-Hydroxyquinolin-5-yl)ethanone 95%
1g
$ 275.00

Alichem
1-(8-Hydroxyquinolin-5-yl)ethanone
5g
$ 529.20

AK Scientific
1-(8-Hydroxyquinolin-5-yl)ethanone
5g
$ 917.00

Total 19 raw suppliers

Chemical Property of 1-(8-Hydroxyquinolin-5-yl)ethanone Edit

Chemical Property:

Vapor Pressure:1.57E-07mmHg at 25°C
Melting Point:110-112°C
Refractive Index:1.4900 (estimate)
Boiling Point:416.5°Cat760mmHg
PKA:3.70±0.10(Predicted)
Flash Point:205.7°C
PSA：50.19000
Density:1.275g/cm³
LogP:2.14300
Storage Temp.:Refrigerator
Solubility.:Chloroform, Methanol
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:187.063328530
Heavy Atom Count:14
Complexity:229

Purity/Quality:

99% ^*data from raw suppliers

Quinacetol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=C2C=CC=NC2=C(C=C1)O
Uses Quinacetol (cas# 2598-31-4) is a compound useful in organic synthesis.

Technology Process of 1-(8-Hydroxyquinolin-5-yl)ethanone

There total 8 articles about 1-(8-Hydroxyquinolin-5-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 148-24-3,24804-14-6
8-quinolinol

: 75-36-5
acetyl chloride

: 2598-31-4
5-acetyl-8-hydroxyquinoline

Guidance literature:: With aluminium trichloride; In nitrobenzene; at 80 - 85 ℃; for 16h;
DOI:10.1246/bcsj.60.2327

Reference yield:

: C₁₅H₂₀INOSi

: 97674-02-7
tributyl(1-ethoxyvinyl)stannane

: 2598-31-4
5-acetyl-8-hydroxyquinoline

Guidance literature:: C₁₅H₂₀INOSi; tributyl(1-ethoxyvinyl)stannane; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In toluene; at 105 - 112 ℃; for 48h; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; at 20 ℃;

With sodium hydrogencarbonate; In tetrahydrofuran; pH=8;