Technology Process of methyl 5-dodecyl-2-fluoro-3-nitrobenzoate
There total 4 articles about methyl 5-dodecyl-2-fluoro-3-nitrobenzoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrakis(triphenylphosphine) palladium(0); potassium carbonate;
In
water; toluene;
at 90 ℃;
for 30h;
Inert atmosphere;
DOI:10.1021/ol201361f
- Guidance literature:
-
Multi-step reaction with 2 steps
1: N-Bromosuccinimide; sulfuric acid; trifluoroacetic acid / 6 h / 45 °C
2: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / water; toluene / 30 h / 90 °C / Inert atmosphere
With
N-Bromosuccinimide; tetrakis(triphenylphosphine) palladium(0); sulfuric acid; potassium carbonate; trifluoroacetic acid;
In
water; toluene;
DOI:10.1021/ol201361f
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: iodine; magnesium / tetrahydrofuran / 12 h / Reflux
1.2: -78 - 20 °C
2.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / water; toluene / 30 h / 90 °C / Inert atmosphere
With
tetrakis(triphenylphosphine) palladium(0); iodine; potassium carbonate; magnesium;
In
tetrahydrofuran; water; toluene;
DOI:10.1021/ol201361f
