3-benzyloxy-16,17-seco-estra-1,3,5⁽¹⁰⁾-triene-16,17-dioic acid

Base Information

• Chemical Name: 3-benzyloxy-16,17-seco-estra-1,3,5⁽¹⁰⁾-triene-16,17-dioic acid
• CAS No.: 415974-44-6
• Molecular Formula: C₂₅H₂₈O₅
• Molecular Weight: 408.494
• Mol file: 415974-44-6.mol

Synonyms:3-benzyloxy-16,17-seco-estra-1,3,5⁽¹⁰⁾-triene-16,17-dioic acid

Chemical Property of 3-benzyloxy-16,17-seco-estra-1,3,5⁽¹⁰⁾-triene-16,17-dioic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-benzyloxy-16,17-seco-estra-1,3,5⁽¹⁰⁾-triene-16,17-dioic acid

There total 3 articles about 3-benzyloxy-16,17-seco-estra-1,3,5⁽¹⁰⁾-triene-16,17-dioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

3-benzyloxyestra-1,3,5(10)-trien-17-one (858-98-0) → 3-benzyloxy-16,17-seco-estra-1,3,5(10)-triene-16,17-dioic acid (415974-44-6)

Guidance literature:

3-benzyloxyestra-1,3,5⁽¹⁰⁾-trien-17-one; With potassium hydroxide; iodine; In methanol; at 20 ℃;

With potassium hydroxide; In methanol; water; for 4h; Heating;

DOI:10.1016/S0968-0896(03)00042-7

Reference yield:

→ 3-benzyloxy-16,17-seco-estra-1,3,5(10)-triene-16,17-dioic acid (415974-44-6)

Guidance literature:

With potassium hypoiodite; Erwaermen des Reaktionsprodukts mit wss.-methanol. Kalilauge;

Reference yield:

→ 3-benzyloxy-16,17-seco-estra-1,3,5(10)-triene-16,17-dioic acid (415974-44-6)

Guidance literature:

3-Benzyloxy-16,17-secooestra-1,3,5(10)-trien-16,17-disaeure-dimethylester, aq.KOH;

DOI:10.1021/jm00301a061

upstream raw materials:

3-benzyloxyestra-1,3,5⁽¹⁰⁾-trien-17-one

Downstream raw materials:

3-benzyloxy-N-(1''-pyridin-3''-ylmethyl)-16,17-seco-estra-1,3,5⁽¹⁰⁾-triene-16,17-imide

3-benzyloxy-16,17-seco-estra-1,3,5⁽¹⁰⁾-triene-16,17-dioic acid dimethyl ester

3-benzyloxy-16,17-seco-estra-1,3,5⁽¹⁰⁾-triene-16,17-imide

3-benzyloxy-N-(4''-tert-butyl-benzyl)-16,17-seco-estra-1,3,5⁽¹⁰⁾-triene-16,17-imide

Refernces

• 1、 Shagufta, Ritesh Singh,Panda, Gautam. "Synthetic studies towards steroid-amino acid hybrids". body text. p. 989 - 995. Retrieved 2009/12/26.