5-ISO-BUTYL-5-METHYLHYDANTOIN

Base Information

• Chemical Name: 5-ISO-BUTYL-5-METHYLHYDANTOIN
• CAS No.: 27886-67-5
• Molecular Formula: C8H14 N2 O2
• Molecular Weight: 170.211
• Mol file: 27886-67-5.mol

Synonyms:Hydantoin,5-isobutyl-5-methyl- (6CI,7CI,8CI); 5-Isobutyl-5-methylhydantoin;Methylisobutylhydantoin; NSC 150463

Chemical Property of 5-ISO-BUTYL-5-METHYLHYDANTOIN

Chemical Property:

• Melting Point: 144.5 °C
• Boiling Point: °Cat760mmHg
• PKA: 8.93±0.10(Predicted)
• Flash Point: °C
• PSA: 58.20000
• Density: 1.043g/cm³
• LogP: 1.28820

Purity/Quality:

99% ^*data from raw suppliers

5-isobutyl-5-methylhydantoin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-ISO-BUTYL-5-METHYLHYDANTOIN

There total 6 articles about 5-ISO-BUTYL-5-METHYLHYDANTOIN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

potassium cyanide + ammonium carbonate (506-87-6,6721-33-1,10361-29-2) + 4-methyl-2-pentanone (108-10-1) → 5-methyl-5-isobutyl-hydantoin (27886-67-5)

Guidance literature:

In ethanol; water; for 0.116667h; Time; Solvent; Microwave irradiation;

DOI:10.1080/00397911.2012.730647

Reference yield:

n-hexan-2-one (591-78-6) → 5-methyl-5-isobutyl-hydantoin (27886-67-5)

Guidance literature:

With potassium cyanide; ethanol; ammonium carbonate;

DOI:10.1021/ja01255a014 DOI:10.1021/jo01189a005

Reference yield:

5-methyl-5-(2-methyl-propenyl)-imidazolidine-2,4-dione → 5-methyl-5-isobutyl-hydantoin (27886-67-5)

Guidance literature:

With ethanol; platinum; Hydrogenation;

DOI:10.1021/jo01189a005

upstream raw materials:

n-hexan-2-one

ethanolamine

hydrogenchloride

4-isobutyl-4-methyl-5-thioxo-imidazolidin-2-one

Downstream raw materials:

2-amino-2,4-dimethyl-valeric acid ethyl ester

4-Isobutyl-4-methyl-2,5-dioxo-imidazolidine-1-carbonitrile

2-amino-2,4-dimethylpentanoic acid

Refernces

• 1、 Safari, Javad,Javadian, Leila. "A one-pot synthesis of 5,5-disubstituted hydantoin derivatives using magnetic Fe3O4 nanoparticles as a reusable heterogeneous catalyst". . p. 1165 - 1171. Retrieved 2013/12/04.