NSC27927

Base Information

• Chemical Name: NSC27927
• CAS No.: 5472-23-1
• Molecular Formula: C19H13NO
• Molecular Weight: 271.318
• Mol file: 5472-23-1.mol

Synonyms:9(10-phenyl)-acridinone;9-Hydro-9-oxo-10-phenylacridine;N-Phenylacridone;10-phenyl-9(10H)-acridone;10-phenyl-9(10H)-acridinon;Phenylacridone;9-Acridanone,10-phenyl;10-phenyl-10H-acridin-9-one;9(10H)-Acridinone,10-phenyl;10-phenylacridin-9(10H)-one;

Chemical Property of NSC27927

Chemical Property:

• Vapor Pressure: 1.56E-07mmHg at 25°C
• Melting Point: 274-279°C
• Boiling Point: 428.1°C at 760 mmHg
• PKA: -5.61±0.20(Predicted)
• Flash Point: 169.6°C
• PSA: 22.00000
• Density: 1.245g/cm³
• LogP: 4.14390
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98% ^*data from raw suppliers

10-Phenyl-9(10H)-acridone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Substrate was reported in the synthesis of oxirane derivatives through a two-step synthesis involving a McMurray reaction with 2-Adamantanone.

Technology Process of NSC27927

There total 46 articles about NSC27927 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

phenyl(2-(phenylamino)phenyl)methanone (23699-69-6) → 10-phenylacridin-9(10H)-one (5472-23-1)

Guidance literature:

With [2,2]bipyridinyl; copper(l) iodide; oxygen; In N,N-dimethyl acetamide; at 140 ℃; for 15h; Sealed tube;

DOI:10.1002/chem.201203859

Reference yield: 97.0%

N,N-diphenylanthranilic acid methyl ester (315179-49-8) → 10-phenylacridin-9(10H)-one (5472-23-1)

Guidance literature:

With boron trifluoride diethyl etherate; In neat (no solvent); at 150 ℃; for 0.0166667h; Microwave irradiation;

DOI:10.1039/c9ra09478d

Reference yield: 93.0%

10-phenyl-9,10-dihydroacridine (10336-24-0) → 10-phenylacridin-9(10H)-one (5472-23-1)

Guidance literature:

10-phenyl-9,10-dihydroacridine; With tetra-O-acetyl riboflavin; oxygen; In acetonitrile; for 0.0333333h; under 760.051 Torr; Green chemistry;

In acetonitrile; at 20 ℃; for 8h; Sealed tube; Irradiation; Green chemistry;

DOI:10.3390/molecules26040974

upstream raw materials:

N-Phenyl-1,2,3,4-tetrahydroacridin-9-one

2-(N,N-diphenylamino)benzoic acid

N,N-dimethylethylenediamine

[1-(2-Diphenylamino-phenyl)-meth-(E)-ylideneaminooxy]-ethaneperoxoic acid tert-butyl ester

Downstream raw materials:

10-phenyl-9,10-dihydroacridine

N-phenyldibenzazepine

Refernces

• 1、 -. "Acridine compound and light-emitting device". Paragraph 0049-0051. . Retrieved 2021/02/06.
• 2、 Chinchilla, Rafael,Torregrosa-Chinillach, Alejandro. "Synthesis of xanthones, thioxanthones and Acridones by a metal-free photocatalytic oxidation using visible light and molecular oxygen". . . Retrieved 2021/06/12.