Talipexole dihydrochloride

Base Information

• Chemical Name: Talipexole dihydrochloride
• CAS No.: 36085-73-1
• Molecular Formula: C10H15N3S^.2(HCl)
• Molecular Weight: 282.23
• Hs Code.: 2934999090
• European Community (EC) Number: 629-837-5
• UNII: 9R6E1D8H1O
• DSSTox Substance ID: DTXSID20189669
• Wikidata: Q27272940
• Mol file: 36085-73-1.mol

Synonyms:2-amino-6-allyl-5,6,7,8-tetrahydro-4H-thiazolo-(5,4-d)azepin-dihydrochloride;6-allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo(4,5-d)azepin dihydrochloride;B HT920;B-HT 920;BHT 920;BHT920;talipexole

Chemical Property of Talipexole dihydrochloride

Chemical Property:

• Appearance/Colour: light yellow solid
• Vapor Pressure: 1.66E-05mmHg at 25°C
• Melting Point: 245 °C
• Boiling Point: 364.6 °C at 760 mmHg
• Flash Point: 174.3 °C
• PSA: 70.39000
• LogP: 3.43500
• Storage Temp.: Desiccate at RT
• Solubility.: H2O: >20 mg/mL
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 281.0520241
• Heavy Atom Count: 16
• Complexity: 210

Purity/Quality:

99% ^*data from raw suppliers

B-HT 920 ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CCN1CCC2=C(CC1)SC(=N2)N.Cl.Cl
• Description: B-HT 920 is a potent agonist of dopamine 2 (D2) receptors (Ki = 5.8 nM) that shows selectivity for D2 over D3 and D4 receptors. It has neuroprotective and regenerative effects in animal models of Parkinson’s disease. B-HT 920 is also an agonist of α2-adrenergic receptors and an antagonist of serotonin-3 (5-HT3; Ki = 0.35 μM) receptors.
• Uses: B-HT 920 DIHYDROCHLORIDE is an alpha 2-Adrenoceptor and dopamine D2-receptor agonist. Used as an antiparkinson reagent