(8S,9S,13S,14S)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-2,17-diol

Base Information

• Chemical Name: (8S,9S,13S,14S)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-2,17-diol
• CAS No.: 26011-40-5
• Molecular Formula: C21H26 O3
• Molecular Weight: 326.436
• Mol file: 26011-40-5.mol

Synonyms:19-Nor-17a-pregna-1,3,5(10)-trien-20-yne-2,17-diol,3-methoxy- (8CI); 17a-Ethynyl-2-hydroxyestradiol 3-methyl ether; 2-Hydroxymestranol

Chemical Property of (8S,9S,13S,14S)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-2,17-diol

Chemical Property:

• Vapor Pressure: 7.21E-10mmHg at 25°C
• Boiling Point: 476°C at 760 mmHg
• PKA: 10.28±0.60(Predicted)
• Flash Point: 241.7°C
• PSA: 49.69000
• Density: 1.22g/cm³
• LogP: 3.62120

Purity/Quality:

99% ^*data from raw suppliers

2-Hydroxy mestranol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): A reproductive hazard.
• Hazard Codes: A reproductive hazard.

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A metabolite of Mestranol A metabolite of Mestranol.

Technology Process of (8S,9S,13S,14S)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-2,17-diol

There total 1 articles about (8S,9S,13S,14S)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-2,17-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

mestranol (72-33-3) → ethinyl estradiol (57-63-6) + 2-hydroxy-mestranol (26011-40-5) + 17a-Ethynyl-2-methoxyestradiol (22415-44-7,26011-46-1) + [3H]-Ethinylestradiol glucuronide (60134-76-1) + 17-ethynyl-3-hydroxy-1,2,3(10)-estratrien-17β-yl-β-D-glucopyranosiduronate (75803-39-3) + 17-ethynyl-1,2,3(10)-estratrien-3,17β-diyl-β-D-glucopyranosiduronate (75812-41-8)

Guidance literature:

Product distribution; metabolism in women in dependence on geographic locality;

DOI:10.1016/0039-128X(80)90001-X

upstream raw materials:

mestranol

Refernces