Prop-1-yn-1-ylcyclopropane

Base Information

• Chemical Name: Prop-1-yn-1-ylcyclopropane
• CAS No.: 35201-01-5
• Molecular Formula: C₆H₈
• Molecular Weight: 80.1295
• Mol file: 35201-01-5.mol

Synonyms:methylcyclopropylacetylene

Chemical Property of Prop-1-yn-1-ylcyclopropane

Chemical Property:

Purity/Quality:

98%min ^*data from raw suppliers

Prop-1-yn-1-ylcyclopropane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Prop-1-yn-1-ylcyclopropane

There total 11 articles about Prop-1-yn-1-ylcyclopropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

Cyclopropylacetylene (6746-94-7) + methyl iodide (74-88-4) → methylcyclopropylacetylene (35201-01-5)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; at 20 ℃; for 3h;

Reference yield:

ethenylidenecyclopropane (27567-84-6) + dimethyl sulfate (77-78-1) → methylcyclopropylacetylene (35201-01-5) + ethylidene-cyclopropane (18631-83-9)

Guidance literature:

ethenylidenecyclopropane; With lithium; In tetrahydrofuran; diethyl ether; at -40 ℃;

dimethyl sulfate; In tetrahydrofuran; diethyl ether;

DOI:10.1016/S0022-328X(01)01195-0

Reference yield:

hexa-3,4-dienyl tosylate (24767-73-5) → methylcyclopropylacetylene (35201-01-5)

Guidance literature:

With sodium acetate; acetic anhydride; In acetic acid;

DOI:10.1021/ja01045a042

upstream raw materials:

diazomethane

pent-1-en-3-yne

5-cyclopropyl-5-methyl-3-nitroso-oxazolidin-2-one

1-(Cyclopropylmethyl)-vinyl-triflat

Downstream raw materials:

4-Cyclopropyl-1,1-diphenyl-3-butin-1-ol

1-benzenesulfonylindole

Refernces

• 1、 Hanack, Michael,Weber, Erhard. "Vinylcations, 39. Zinc Chloride Catalysed Addition of Hydrogen Chloride to Cyclopropylalkynes". . p. 777 - 797. Retrieved 2007/10/02.