Silicic acid (H4SiO4), tetrakis(2,2,2-trifluoroethyl) ester

Base Information

• Chemical Name: Silicic acid (H4SiO4), tetrakis(2,2,2-trifluoroethyl) ester
• CAS No.: 338-39-6
• Molecular Formula: C8H8 F12 O4 Si
• Molecular Weight: 424.22
• Hs Code.: 2915900090
• DSSTox Substance ID: DTXSID70955376
• Nikkaji Number: J719.407B
• Wikidata: Q82934933
• Mol file: 338-39-6.mol

Synonyms:338-39-6;Silicic acid (H4SiO4), tetrakis(2,2,2-trifluoroethyl) ester;Tetrakis(2,2,2-trifluoroethoxy)silane;Ethanol, 2,2,2-trifluoro-, tetraester with silicic acid (H4SiO4);tetrakis(2,2,2-trifluoroethyl) orthosilicate;tetra(trifluoroethoxy)silane;C8H8F12O4Si;SCHEMBL996574;C8-H8-F12-O4-Si;DTXSID70955376;MRBWGPMSUYEXDQ-UHFFFAOYSA-N

Chemical Property of Silicic acid (H4SiO4), tetrakis(2,2,2-trifluoroethyl) ester

Chemical Property:

• PSA: 36.92000
• LogP: 3.73760
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 16
• Rotatable Bond Count: 8
• Exact Mass: 424.0000232
• Heavy Atom Count: 25
• Complexity: 322

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(F)(F)F)O[Si](OCC(F)(F)F)(OCC(F)(F)F)OCC(F)(F)F

Technology Process of Silicic acid (H4SiO4), tetrakis(2,2,2-trifluoroethyl) ester

There total 2 articles about Silicic acid (H4SiO4), tetrakis(2,2,2-trifluoroethyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(CF3CH2O)3Si(NHNHC6H5) + titanium tetrachloride (7550-45-0) → Si(NHNHC6H5)4(TiCl4) (122953-84-8) + tetrakis(2,2,2-trifluoroethoxy)silane (338-39-6)

Guidance literature:

In Petroleum ether; dropwise addn. of soln. of TiCl4 in petroleum ether (40-60°C) to soln. of 1-trialkoxysilyl 2-phenylhydrazine (equimolar amts., 0 to -10°C, under dry nitrogen), ppt. filtered in a cold atm. of dry N2; washed, dried under reduced pressure; elem. anal.;

DOI:10.1016/S0020-1693(00)80899-3

Reference yield: 88.0%

(CF3CH2O)3Si(NHNHC6H5) + tin(IV) chloride (7646-78-8) → Si(NHNHC6H5)4(SnCl4) (122953-85-9) + tetrakis(2,2,2-trifluoroethoxy)silane (338-39-6)

Guidance literature:

In Petroleum ether; dropwise addn. of soln. of SnCl4 in petroleum ether (40-60°C) to soln. of 1-trialkoxysilyl 2-phenylhydrazine (equimolar amts., 0 to -10°C, under dry nitrogen), ppt. filtered in a cold atm. of dry N2; washed, dried under reduced pressure; elem. anal.;

DOI:10.1016/S0020-1693(00)80899-3

Reference yield: 93.0%

tetrakis(2,2,2-trifluoroethoxy)silane (338-39-6) + 3-Phenylpropionic acid (501-52-0) → 2,2,2-trifluoroethyl 3-phenylpropanoate (23522-66-9)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 20 ℃; for 24h;

DOI:10.1246/cl.2005.1586

upstream raw materials:

titanium tetrachloride

tin(IV) chloride

Downstream raw materials:

1,2,2,3,3,4,4,5,5,6,6-Undecafluoro-cyclohexanecarboxylic acid 2,2,2-trifluoro-ethyl ester

2,2,2-trifluoroethyl 3-phenylpropanoate

3-phenyl-N-(1-phenylethyl)propanamide