methyl N-ethylglycinate hydrochloride

Base Information

• Chemical Name: methyl N-ethylglycinate hydrochloride
• CAS No.: 1121527-61-4
• Molecular Formula: C₅H₁₁NO₂*ClH
• Molecular Weight: 153.609
• Hs Code.: 2922498590
• Mol file: 1121527-61-4.mol

Synonyms:methyl N-ethylglycinate hydrochloride

Chemical Property of methyl N-ethylglycinate hydrochloride

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Ethylamino-aceticAcidMethylEsterHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of methyl N-ethylglycinate hydrochloride

There total 2 articles about methyl N-ethylglycinate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methanol (67-56-1) + N-ethylglycine (627-01-0) → methyl N-ethylglycinate hydrochloride (1121527-61-4)

Guidance literature:

With thionyl chloride; at 0 - 25 ℃; for 4h;

Reference yield: 81.0%

N-(tert-buytoxycarbonyl)-N-ethylglycine (149794-10-5) + diazomethyl-trimethyl-silane (18107-18-1) → methyl N-ethylglycinate hydrochloride (1121527-61-4)

Guidance literature:

N-(tert-buytoxycarbonyl)-N-ethylglycine; diazomethyl-trimethyl-silane; In methanol; at 0 - 20 ℃; for 0.333333h;

With hydrogenchloride; In acetic acid; at 20 ℃; for 2h;

Reference yield: 30.0%

methyl N-ethylglycinate hydrochloride (1121527-61-4) + 2-butyl-3-({4-[3-(dibutylamino)propyl]phenyl}carbonyl)indolizine-7-carboxylic acid (1376436-87-1) → methyl N-{[2-butyl-3-({4-[3-(dibutylamino)propyl]phenyl}carbonyl)indolizin-7-yl]carbonyl}-N-ethylglycinate hydrochloride (1376436-83-7)

Guidance literature:

upstream raw materials:

methanol

N-ethylglycine

N-(tert-buytoxycarbonyl)-N-ethylglycine

diazomethyl-trimethyl-silane

Downstream raw materials:

methyl N-{[2-butyl-3-({4-[3-(dibutylamino)propyl]phenyl}carbonyl)indolizin-7-yl]carbonyl}-N-ethylglycinate hydrochloride

Refernces

• 1、 -. "Novel Compounds 002". Page/Page column 26. . Retrieved 2009/04/24.