Amino-furan-2-yl-acetic acid

Base Information

• Chemical Name: Amino-furan-2-yl-acetic acid
• CAS No.: 17119-54-9
• Molecular Formula: C6H7NO3
• Molecular Weight: 141.12
• Hs Code.: 2932190090
• NSC Number: 170418
• DSSTox Substance ID: DTXSID20305362
• Mol file: 17119-54-9.mol

Synonyms:17119-54-9;2-amino-2-(furan-2-yl)acetic acid;Amino-furan-2-yl-acetic acid;Amino(2-furyl)acetic acid;2-Furanacetic acid, |A-amino-;Amino-furan-2-ylacetic acid;NSC170418;2-Furanacetic acid,a-amino-;alpha-Amino-2-furanacetic acid;alpha-amino-2-furylacetic acid;SCHEMBL2455073;DTXSID20305362;DYFYPSCJKBYYNK-UHFFFAOYSA-N;110727-83-8;2-amino-2-(furan-2-yl)aceticacid;2-AMINO-2-FURANACETIC ACID;MFCD00030618;AKOS015914182;AB01510;AB14775;NSC-170418;CS-0328547;FT-0601879;EN300-103081;F78735;(2R)-2-AMINO-2-(2-FURYL)ACETIC ACID;Amino-furan-2-yl-acetic acid (H-DL-Gly(Fur-2-yl)-OH)

Chemical Property of Amino-furan-2-yl-acetic acid

Chemical Property:

• Vapor Pressure: 0.0343mmHg at 25°C
• Refractive Index: 1.55
• Boiling Point: 231.7 °C at 760 mmHg
• Flash Point: 93.9 °C
• PSA: 76.46000
• Density: 1.355g/cm³
• LogP: 1.06430
• XLogP3: -2.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 141.042593085
• Heavy Atom Count: 10
• Complexity: 137

Purity/Quality:

98%min ^*data from raw suppliers

Amino-furan-2-yl-aceticacid 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=COC(=C1)C(C(=O)O)N

Technology Process of Amino-furan-2-yl-acetic acid

There total 4 articles about Amino-furan-2-yl-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(+/-)ethyl furanglycinate (120133-80-4) → DL-2-amino-2-(furan-2-yl)acetic acid (17119-54-9,64757-64-8)

Guidance literature:

With lithium hydroxide; In water; Yield given; Ambient temperature;

DOI:10.1016/S0040-4020(01)86045-2

Reference yield:

ethyl α-<(diphenylmethylene)amino>-(+/-)-2-furanacetate (120133-79-1) → DL-2-amino-2-(furan-2-yl)acetic acid (17119-54-9,64757-64-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 0.1 M hydrochloric acid / H₂O / 3 h / Ambient temperature

2: 20 percent lithium hydroxide / H₂O / Ambient temperature

With hydrogenchloride; lithium hydroxide; In water;

DOI:10.1016/S0040-4020(01)86045-2

Reference yield:

→ DL-2-amino-2-(furan-2-yl)acetic acid (17119-54-9,64757-64-8)

Guidance literature:

With barium dihydroxide; water;

upstream raw materials:

(+/-)ethyl furanglycinate

ethyl α-<(diphenylmethylene)amino>-(+/-)-2-furanacetate

Downstream raw materials:

furan-2-yl-(toluene-4-sulfonylamino)-acetic acid

N-[1-(2-furyl)-2-(hydroxyethyl)]-4-methylbenzenesulfonamide

(S)-α-Benzyl-α-(2-furyl)glycin

(3S,6S)-3-Benzyl-3-(2-furyl)-3,6-dihydro-6-isopropyl-5-methoxy-1,4-oxazin-2-on

Refernces