C₂₂H₂₀FNO₃

Base Information

• Chemical Name: C₂₂H₂₀FNO₃
• CAS No.: 1160947-50-1
• Molecular Formula: C₂₂H₂₀FNO₃
• Molecular Weight: 365.404
• Mol file: 1160947-50-1.mol

Synonyms:C₂₂H₂₀FNO₃

Chemical Property of C₂₂H₂₀FNO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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Technology Process of C₂₂H₂₀FNO₃

There total 1 articles about C₂₂H₂₀FNO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C14H13NO2 (1160947-49-8) + ((1-(4-fluorophenyl)vinyl)oxy)trimethylsilane (58518-77-7) → C22H20FNO3 (1160947-50-1)

Guidance literature:

C₁₄H₁₃NO₂; ((1-(4-fluorophenyl)vinyl)oxy)trimethylsilane; With boron trifluoride diethyl etherate; In dichloromethane; at -78 ℃;

With water; sodium hydrogencarbonate; In dichloromethane;

Reference yield:

C22H20FNO3 (1160947-50-1) → C15H16FNO2 (1160947-52-3)

Guidance literature:

C₂₂H₂₀FNO₃; With methanesulfonyl chloride; triethylamine; In dichloromethane; at 0 ℃; for 1h;

With silica gel; In dichloromethane; for 1h;

With sodium tetrahydroborate; water; hydrogen; ammonium chloride; palladium 10% on activated carbon; more than 3 stages;

upstream raw materials:

C₁₄H₁₃NO₂

((1-(4-fluorophenyl)vinyl)oxy)trimethylsilane

Downstream raw materials:

C₁₅H₁₆FNO₂

Refernces