Technology Process of C18H24NO3P
There total 4 articles about C18H24NO3P which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
In
toluene;
at 125 - 135 ℃;
for 2h;
Inert atmosphere;
Molecular sieve;
DOI:10.1021/ol300366e
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium phosphate; copper(ll) sulfate pentahydrate; 1,10-Phenanthroline / toluene / 48 h / 60 - 70 °C / Inert atmosphere
2: toluene / 2 h / 125 - 135 °C / Inert atmosphere; Molecular sieve
With
potassium phosphate; 1,10-Phenanthroline; copper(ll) sulfate pentahydrate;
In
toluene;
2: aza-Claisen rearrangement-carbocyclization;
DOI:10.1021/ol300366e
- Guidance literature:
-
Multi-step reaction with 3 steps
1: triethylamine / dichloromethane / 47 h / 0 - 20 °C / Inert atmosphere
2: potassium phosphate; copper(ll) sulfate pentahydrate; 1,10-Phenanthroline / toluene / 48 h / 60 - 70 °C / Inert atmosphere
3: toluene / 2 h / 125 - 135 °C / Inert atmosphere; Molecular sieve
With
potassium phosphate; 1,10-Phenanthroline; copper(ll) sulfate pentahydrate; triethylamine;
In
dichloromethane; toluene;
3: aza-Claisen rearrangement-carbocyclization;
DOI:10.1021/ol300366e