C₂₄H₂₈N₄O₆S

Base Information

• Chemical Name: C₂₄H₂₈N₄O₆S
• CAS No.: 1049797-22-9
• Molecular Formula: C₂₄H₂₈N₄O₆S
• Molecular Weight: 500.576
• Mol file: 1049797-22-9.mol

Synonyms:C₂₄H₂₈N₄O₆S

Chemical Property of C₂₄H₂₈N₄O₆S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₂₈N₄O₆S

There total 8 articles about C₂₄H₂₈N₄O₆S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-cyclohexyl-6-(N,N-dimethylsulfamoylcarbamoyl)-2-(2-formyl-4-methoxyphenyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridine 7-oxide (1049796-92-0) → C24H28N4O6S (1049797-22-9)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 22h; Heating / reflux;

Reference yield:

3-cyclohexenyl-1H-pyrrolo[2,3-b]pyridine (494799-64-3) → C24H28N4O6S (1049797-22-9)

Guidance literature:

Multi-step reaction with 6 steps

1.1: hydrogen / 20% Pd(OH)2 on carbon / tetrahydrofuran; ethanol / 144 h

2.1: pyridinium hydrobromide perbromide / tetrahydrofuran / 4 h / Heating / reflux

3.1: 3-chloro-benzenecarboperoxoic acid / 1,2-dimethoxyethane / 1 h / 20 °C

3.2: 1.17 h / 20 °C

4.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -78 °C

4.2: 2 h / 50 °C

4.3: 2.5 h / 20 °C

5.1: dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate / palladium diacetate / toluene / 2 h / Heating / reflux

6.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 22 h / Heating / reflux

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; pyridinium hydrobromide perbromide; tetrabutyl ammonium fluoride; hydrogen; 3-chloro-benzenecarboperoxoic acid; lithium diisopropyl amide; palladium diacetate; 20% Pd(OH)2 on carbon; In tetrahydrofuran; 1,2-dimethoxyethane; ethanol; toluene; 5.1: Suzuki Coupling;

Reference yield:

3-cyclohexyl-1H-pyrrolo[2,3-b]pyridine (494799-65-4) → C24H28N4O6S (1049797-22-9)

Guidance literature:

Multi-step reaction with 5 steps

1.1: pyridinium hydrobromide perbromide / tetrahydrofuran / 4 h / Heating / reflux

2.1: 3-chloro-benzenecarboperoxoic acid / 1,2-dimethoxyethane / 1 h / 20 °C

2.2: 1.17 h / 20 °C

3.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -78 °C

3.2: 2 h / 50 °C

3.3: 2.5 h / 20 °C

4.1: dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate / palladium diacetate / toluene / 2 h / Heating / reflux

5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 22 h / Heating / reflux

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; pyridinium hydrobromide perbromide; tetrabutyl ammonium fluoride; 3-chloro-benzenecarboperoxoic acid; lithium diisopropyl amide; palladium diacetate; In tetrahydrofuran; 1,2-dimethoxyethane; toluene; 4.1: Suzuki Coupling;

upstream raw materials:

3-cyclohexyl-6-(N,N-dimethylsulfamoylcarbamoyl)-2-(2-formyl-4-methoxyphenyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridine 7-oxide

3-cyclohexenyl-1H-pyrrolo[2,3-b]pyridine

3-cyclohexyl-1H-pyrrolo[2,3-b]pyridine

7-Azaindole

Downstream raw materials:

Methyl 13-cyclohexyl-10-((((dimethylamino)sulfonyl)amino)carbonyl)-3-(methyloxy)-7H-pyrido[3',2':4,5]pyrrolo[2,1-a][2]benzazepine-6-carboxylate 9-oxide

Refernces