Technology Process of Sphaerophorin
There total 8 articles about Sphaerophorin which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
ethyl acetate;
for 24h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 96 percent / K2CO3 / acetone / 22 h / Heating
2: aq. KOH / dimethylsulfoxide / 3 h / 95 °C
3: 39 percent / trifluoroacetic anhydride / toluene / 21 h / Ambient temperature
4: 35 percent / H2 / 10percent Pd/C / ethyl acetate / 24 h
With
potassium hydroxide; hydrogen; potassium carbonate; trifluoroacetic anhydride;
palladium on activated charcoal;
In
dimethyl sulfoxide; ethyl acetate; acetone; toluene;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 39 percent / trifluoroacetic anhydride / toluene / 21 h / Ambient temperature
2: 35 percent / H2 / 10percent Pd/C / ethyl acetate / 24 h
With
hydrogen; trifluoroacetic anhydride;
palladium on activated charcoal;
In
ethyl acetate; toluene;
