Eromycin

Base Information

• Chemical Name: Eromycin
• CAS No.: 3521-62-8
• Molecular Formula: C52H97NO18S
• Molecular Weight: 1000.34
• Hs Code.: 29419000
• European Community (EC) Number: 222-532-4
• Mol file: 3521-62-8.mol

Synonyms:Eromycin;Erythromycin Estolate;Erythromycin Propionate Dodecyl Sulfate;Erythromycin Propionate Lauryl Sulfate;Erythromycin Propionate Monododecyl Sulfate;Estolate, Erythromycin;Ilosone;Lauromicina

Chemical Property of Eromycin

Chemical Property:

• Appearance/Colour: Long needles
• Vapor Pressure: 8.87E-32mmHg at 25°C
• Melting Point: 135-140 °C dec.
• Refractive Index: 1.6550 (estimate)
• Boiling Point: 827.7 °C at 760 mmHg
• PKA: 6.9(at 25℃)
• Flash Point: 454.4 °C
• PSA: 271.96000
• Density: 1.0053 (rough estimate)
• LogP: 7.55400
• Storage Temp.: -20°C Freezer
• Sensitive.: Light Sensitive
• Solubility.: chloroform: soluble4.0ML, clear, colorless (200 mg + 4.0 mL Chlo
• Water Solubility.: Freely soluble in organic solvents, practically insoluble in water /n
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 19
• Rotatable Bond Count: 22
• Exact Mass: 1055.64263642
• Heavy Atom Count: 72
• Complexity: 1550

Purity/Quality:

99% ^*data from raw suppliers

Erythromycin estolate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,Xi
• Hazard Codes: Xn,Xi
• Statements: 22-42/43-36/37/38
• Safety Statements: 22-36-26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCOS(=O)(=O)O.CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)OC(=O)CC)(C)O)C)C)O)(C)O
• Isomeric SMILES: CCCCCCCCCCCCOS(=O)(=O)O.CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H](C([C@@H]([C@H](C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)OC(=O)CC)(C)O)C)C)O)(C)O
• Uses: Used as an antibacterial agent. LD50 >5000 mg/kg for oral administration to rats Macrolides Antibiotics Used as an antibacterial agent. LD50 >5000 mg/kg for oral administration to rats.
• Therapeutic Function: Antibacterial

Technology Process of Eromycin

There total 1 articles about Eromycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sodium dodecyl-sulfate (151-21-3) + erythromycin (114-07-8) → erythromycin estolate (3521-62-8)

Guidance literature:

With phosphate buffer; pH=5.5;

DOI:10.1159/000211363

upstream raw materials:

sodium dodecyl-sulfate

erythromycin

Refernces