Vidarabine phosphate

Base Information Edit

Chemical Name:Vidarabine phosphate
CAS No.:29984-33-6
Molecular Formula:C10H14N5O7P
Molecular Weight:347.224
Hs Code.:29400090
European Community (EC) Number:249-990-8
UNII:106XV160TZ
DSSTox Substance ID:DTXSID401009318
Nikkaji Number:J17.878K
Wikipedia:Vidarabine_phosphate
Wikidata:Q6607436
NCI Thesaurus Code:C90789
ChEMBL ID:CHEMBL1230732
Mol file:29984-33-6.mol

Synonyms:9-(5-O-Phosphono-beta-D-arabinofuranosyl)-9H-purin-6-amine;Adenine Arabinoside Monophosphate;Ara AMP;Ara-AMP;Arabinofuranosyladenine Monophosphate;Monophosphate, Adenine Arabinoside;Monophosphate, Arabinofuranosyladenine;Monophosphate, Vidarabine;Phosphate, Vidarabine;Vidarabine Monophosphate;Vidarabine Phosphate

Suppliers and Price of Vidarabine phosphate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Vidarabinemonophosphate 97%
5g
$ 200.00

Biosynth Carbosynth
9-(b-D-Arabinofuranosyl)adenine 5'-monophosphate
25 g
$ 475.00

Biosynth Carbosynth
9-(b-D-Arabinofuranosyl)adenine 5'-monophosphate
10 g
$ 220.00

Biosynth Carbosynth
9-(b-D-Arabinofuranosyl)adenine 5'-monophosphate
2 g
$ 60.00

Biosynth Carbosynth
9-(b-D-Arabinofuranosyl)adenine 5'-monophosphate
1 g
$ 40.00

Biosynth Carbosynth
9-(b-D-Arabinofuranosyl)adenine 5'-monophosphate
5 g
$ 115.00

American Custom Chemicals Corporation
ADENINE-9-BETA-D-ARABINOFURANOSIDE-5'-MONOPHOSPHATE 95.00%
10MG
$ 622.19

Alfa Aesar
9-beta-D-Arabinofuranosyladenine-5'-monophosphate, 99%
5g
$ 63.70

Alfa Aesar
9-beta-D-Arabinofuranosyladenine-5'-monophosphate, 99%
1g
$ 22.10

AK Scientific
Vidarabinemonophosphate
5g
$ 205.00

Total 97 raw suppliers

Chemical Property of Vidarabine phosphate Edit

Chemical Property:

Appearance/Colour:White crystalline powder.
Vapor Pressure:6.7E-27mmHg at 25°C
Melting Point:213 °C
Boiling Point:798.5 °C at 760 mmHg
PKA:1.86±0.10(Predicted)
Flash Point:436.7 °C
PSA：195.88000
Density:2.32 g/cm³
LogP:-1.28180
Storage Temp.:Store at 0°C
Water Solubility.:Soluble in water at 4mg/ml
XLogP3:-3.5
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:4
Exact Mass:347.06308480
Heavy Atom Count:23
Complexity:481

Purity/Quality:

99% ^*data from raw suppliers

Vidarabinemonophosphate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn, T, Xi
Hazard Codes:Xn,T,Xi
Statements: 20/22-40-23/24/25-36/37/38
Safety Statements: 37/39-24/25-45-36/37/39-22-36-26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O)N
Isomeric SMILES:C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O)N
Description Vidarabine monophosphate, chemical name: 9-(5-O-Phosphono-beta-D-arabinofuranosyl)adenine is an anti deoxyribonucleic acid virus drug. IVidarabine triphosphate directly inhibits DNA polymerase and also acts as a chain terminator in DNA replication. An adenosine monophosphate analog in which ribose is replaced by an arabinose moiety. It is the monophosphate ester of VIDARABINE with antiviral and possibly antineoplastic properties.
Uses Antiviral. Disrupts viral DNA synthesis. Competitive viral DNA polymerase inhibitor. Active against herpes simplex and varicella zoster viruses in vivo.

Technology Process of Vidarabine phosphate

There total 23 articles about Vidarabine phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%