2,5-bis-(phenylhydroxymethyl)-3,4-dioctyloxythiophene

Base Information

• Chemical Name: 2,5-bis-(phenylhydroxymethyl)-3,4-dioctyloxythiophene
• CAS No.: 496801-13-9
• Molecular Formula: C₃₄H₄₈O₄S
• Molecular Weight: 552.819
• Mol file: 496801-13-9.mol

Synonyms:2,5-bis-(phenylhydroxymethyl)-3,4-dioctyloxythiophene

Chemical Property of 2,5-bis-(phenylhydroxymethyl)-3,4-dioctyloxythiophene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,5-bis-(phenylhydroxymethyl)-3,4-dioctyloxythiophene

There total 4 articles about 2,5-bis-(phenylhydroxymethyl)-3,4-dioctyloxythiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

benzaldehyde (100-52-7) + 3,4-di-n-octoxythiophene (207802-19-5) → (3,4-bis-octyloxy-thiophen-2-yl)-phenyl-methanol + 2,5-bis-(phenylhydroxymethyl)-3,4-dioctyloxythiophene (496801-13-9)

Guidance literature:

With N,N,N,N,-tetramethylethylenediamine; In tetrahydrofuran; hexane; Heating;

DOI:10.1016/j.tet.2004.09.008

Reference yield:

2,3-dimethoxythiophene (51792-34-8) → 2,5-bis-(phenylhydroxymethyl)-3,4-dioctyloxythiophene (496801-13-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 67 percent / p-toluenesulfonic acid / toluene / 28 h / 90 °C

2: 28 percent / N,N,N',N'-tetramethylethylenediamine / hexane; tetrahydrofuran / Heating

With N,N,N,N,-tetramethylethylenediamine; toluene-4-sulfonic acid; In tetrahydrofuran; hexane; toluene;

DOI:10.1016/j.tet.2004.09.008

Reference yield:

3,4-dimethoxythiophene-2,5-dicarboxylic acid (177364-96-4) → 2,5-bis-(phenylhydroxymethyl)-3,4-dioctyloxythiophene (496801-13-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 56 percent / copper chromite; quinoline / 4 h / 160 °C

2: 67 percent / p-toluenesulfonic acid / toluene / 28 h / 90 °C

3: 28 percent / N,N,N',N'-tetramethylethylenediamine / hexane; tetrahydrofuran / Heating

With quinoline; copper chromite; N,N,N,N,-tetramethylethylenediamine; toluene-4-sulfonic acid; In tetrahydrofuran; hexane; toluene;

DOI:10.1016/j.tet.2004.09.008

upstream raw materials:

benzaldehyde

3,4-di-n-octoxythiophene

2,3-dimethoxythiophene

3,4-dimethoxythiophene-2,5-dicarboxylic acid

Downstream raw materials:

5,15,10,20-tetraphenylporphyrin

Refernces

• 1、 Agarwal, Neeraj,Mishra, Sarada P.,Kumar, Anil,Hung,Ravikanth. "Synthesis and crystal structure of 2,3,12,13-tetraalkoxy-21,23-dithiaporphyrins". . p. 2642 - 2643. Retrieved 2007/10/03.