Fmoc-Arg(Pbf)-OH

Base Information

• Chemical Name: Fmoc-Arg(Pbf)-OH
• CAS No.: 154445-77-9
• Molecular Formula: C34H40N4O7S
• Molecular Weight: 648.78
• Hs Code.: 2935 90 90
• European Community (EC) Number: 604-954-4
• DSSTox Substance ID: DTXSID10463228
• Nikkaji Number: J2.211.521I
• Mol file: 154445-77-9.mol

Synonyms:Fmoc-Arg(Pbf)-OH;154445-77-9;(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)pentanoic acid;(2S)-5-[[amino-[(2,2,4,6,7-pentamethyl-3H-1-benzofuran-5-yl)sulfonylamino]methylidene]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoic acid;Nalpha-Fmoc-Nomega-Pbf-L-arginine;MFCD00235804;Fmoc-L-arg(pbf)-OH;fmoc-arg(pbf);Na-Fmoc-Nw-Pbf-L-arginine;SCHEMBL3431396;SCHEMBL8302353;DTXSID10463228;HNICLNKVURBTKV-NDEPHWFRSA-N;AMY31277;HY-Y1636;AKOS015888151;AKOS015924226;AKOS032949739;CS-W019715;N-alpha-Fmoc-N-g-(2,2,4,6,7-pentamethyl-dihydrobenzofuran-5-sulfonyl)-L-arginine;Nalpha-Fmoc-Nomega-(2,2,4,6,7-pentamethyldihydro-benzofuran-5-sulfonyl)-L-arginine;DS-13757;F0729;Fmoc-Arg(Pbf)-OH, >=98.0% (HPLC);EN300-67540;M03398;A809534;J-300031;Na-Fmoc-Nw-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine;N-alpha-Fmoc-N'-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine;Nalpha-Fmoc-Nomega-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine;(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-{N'-[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]carbamimidamido}pentanoic acid;(2S)-5-[[amino-[(2,2,4,6,7-pentamethyl-3H-benzofuran-5-yl)sulfonylamino]methylene]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoic acid;(S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-5-(3-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-ylsulfonyl)guanidino)pentanoic acid;N2-(((9H-fluoren-9-yl)methoxy)carbonyl)-Nw-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)-L-arginine;Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nomega-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine;Nalpha-Fmoc-Nomega-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzo[b]furan-5-ylsulfonyl)-L-arginine

Chemical Property of Fmoc-Arg(Pbf)-OH

Chemical Property:

• Appearance/Colour: White or off-white powder
• Melting Point: 132 °C
• Refractive Index: 1.648
• PKA: 3.83±0.21(Predicted)
• PSA: 175.29000
• Density: 1.37 g/cm³
• LogP: 7.25330
• Storage Temp.: −20°C
• Solubility.: DMF (Sparingly), DMSO (Slightly), Methanol (Slightly)
• XLogP3: 5.1
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 12
• Exact Mass: 648.26177080
• Heavy Atom Count: 46
• Complexity: 1210

Purity/Quality:

99%min ^*data from raw suppliers

Fmoc-Arg(Pbf)-OH ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C(=C(C2=C1OC(C2)(C)C)C)S(=O)(=O)NC(=NCCCC(C(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35)N)C
• Isomeric SMILES: CC1=C(C(=C(C2=C1OC(C2)(C)C)C)S(=O)(=O)NC(=NCCC[C@@H](C(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35)N)C
• Uses: Fmoc-Arg(Pbf)-OH, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance. Fmoc-Arg(Pbf)-OH is a Fmoc-protected amino acid derivative that can be used to create arginine-containing peptides. The 2,2,4,6,7-pentamethyIdlhydrobenzofuran-5-sulfonyl group (Pbf) can be easily cleaved by trifluoroacetic acid (TFA).