2-nitrophenyl 4-nitrophenyl disulfide

Base Information

• Chemical Name: 2-nitrophenyl 4-nitrophenyl disulfide
• CAS No.: 408351-60-0
• Molecular Formula: C₁₂H₈N₂O₄S₂
• Molecular Weight: 308.339
• Mol file: 408351-60-0.mol

Synonyms:2-nitrophenyl 4-nitrophenyl disulfide

Chemical Property of 2-nitrophenyl 4-nitrophenyl disulfide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-nitrophenyl 4-nitrophenyl disulfide

There total 5 articles about 2-nitrophenyl 4-nitrophenyl disulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

N-(2-nitrobenzenesulfenyl)-piperidine (66552-58-7) + 1-acetylsulfanyl-4-nitro-benzene (15119-62-7) → 1-piperidin-1-yl-ethanone (618-42-8) + 2-nitrophenyl 4-nitrophenyl disulfide (408351-60-0)

Guidance literature:

With triphenylphosphine; at 18 - 20 ℃;

Reference yield:

bis(2-nitrophenyl)disulfide (1155-00-6) + di(p-nitrophenyl) disulfide (100-32-3) → 2-nitrophenyl 4-nitrophenyl disulfide (408351-60-0)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; Milling;

DOI:10.1002/ijch.202100090

Reference yield:

2-nitrobenzenesulfenyl bromide (22024-99-3) → 2-nitrophenyl 4-nitrophenyl disulfide (408351-60-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 88 percent / triethylamine / CH₂Cl₂ / 24 h / 18 - 20 °C

2: triphenylphosphine / 18 - 20 °C

With triethylamine; triphenylphosphine; In dichloromethane;

upstream raw materials:

N-(2-nitrobenzenesulfenyl)-piperidine

1-acetylsulfanyl-4-nitro-benzene

2-nitrobenzenesulfenyl chloride

2-nitrobenzenesulfenyl bromide

Downstream raw materials:

bis(2-nitrophenyl)disulfide

di(p-nitrophenyl) disulfide

Refernces

• 1、 Belenguer, Ana M.,Michalchuk, Adam A. L.,Lampronti, Giulio I.,Sanders, Jeremy K. M.. "Using Solid Catalysts in Disulfide-Based Dynamic Combinatorial Solution- and Mechanochemistry". . . Retrieved 2021/12/27.
• 2、 Parfenov, E. A.,Fomin, V. A.. "PARTICIPATION OF ELECTRONIC ORGANIC COMPOUNDS OF DIVALENT SULFUR IN CATALYTIC CONVERSIONS. II. CATALYTIC EXCHANGE REACTION OF N-MONOSULFENYLATED AMINES WITH S-ESTERS OF THIOCARBOXYLIC ACID". . p. 947 - 953. Retrieved 2007/10/02.