methyl 2-(4-t-butylphenyl)butanoate

Base Information

• Chemical Name: methyl 2-(4-t-butylphenyl)butanoate
• CAS No.: 211314-95-3
• Molecular Formula: C₁₅H₂₂O₂
• Molecular Weight: 234.338
• Mol file: 211314-95-3.mol

Synonyms:methyl 2-(4-t-butylphenyl)butanoate

Chemical Property of methyl 2-(4-t-butylphenyl)butanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of methyl 2-(4-t-butylphenyl)butanoate

There total 1 articles about methyl 2-(4-t-butylphenyl)butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl bromide (74-96-4) + methyl 2-(4-tert-butylphenyl)acetate (3549-23-3) → methyl 2-(4-t-butylphenyl)butanoate (211314-95-3)

Guidance literature:

methyl 2-(4-tert-butylphenyl)acetate; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃;

ethyl bromide; In tetrahydrofuran; at -78 ℃; for 2h; Further stages.;

DOI:10.1021/jm0002836

Reference yield:

methyl 2-(4-t-butylphenyl)butanoate (211314-95-3) → 2-(4-(tert-butyl)phenyl)butanoic acid (211314-96-4)

Guidance literature:

With lithium hydroxide; In tetrahydrofuran; methanol; water; at 20 ℃;

DOI:10.1021/jm0002836

Reference yield:

methyl 2-(4-t-butylphenyl)butanoate (211314-95-3) → 2-(4-t-butylphenyl)butylamine (211315-01-4)

Guidance literature:

Multi-step reaction with 4 steps

1: LiOH / H₂O; methanol; tetrahydrofuran / 20 °C

2: (ClCO)2 / CH₂Cl₂ / 2 h / 20 °C

3: NH₄OH / methanol / 20 °C

4: BH₃*THF / tetrahydrofuran / 20 °C

With lithium hydroxide; ammonium hydroxide; borane-THF; oxalyl dichloride; In tetrahydrofuran; methanol; dichloromethane; water;

DOI:10.1021/jm0002836

upstream raw materials:

ethyl bromide

methyl 2-(4-tert-butylphenyl)acetate

Downstream raw materials:

2-(4-(tert-butyl)phenyl)butanoic acid

2-(4-t-butylphenyl)butylamine

2-(4-t-butylphenyl)butanamide

Refernces