Fmoc-L-tert-leucine

Base Information Edit

Chemical Name:Fmoc-L-tert-leucine
CAS No.:132684-60-7
Molecular Formula:C21H23NO4
Molecular Weight:353.418
Hs Code.:29242990
European Community (EC) Number:812-016-2
DSSTox Substance ID:DTXSID70359658
Nikkaji Number:J1.831.010D
Wikidata:Q72478945
Mol file:132684-60-7.mol

Synonyms:132684-60-7;Fmoc-Tle-OH;Fmoc-L-tert-leucine;Fmoc-tBu-Gly-OH;(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3,3-dimethylbutanoic acid;(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3,3-dimethylbutanoic acid;Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-methyl-;fmoc-l-alpha-t-butylglycine;Fmoc-L-tert.leucine;fmoc-t-leucine;MFCD00065649;Fmoc-L-tert leucine;SCHEMBL1253102;DTXSID70359658;VZOHGJIGTNUNNC-GOSISDBHSA-N;Fmoc-tBu-Gly-OH, >=98.0%;(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3,3-dimethyl-butanoic acid;AKOS010367902;AM82576;CS-W009804;HY-W009088;DS-15709;F1251;EN300-258181;F14567;A806475;J-300342;N-alpha-(9-Fluorenylmethyloxycarbonyl-L-tert-leucine;N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tert-leucine;L-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-methyl-;(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3,3-dimethylbutanoic acid

Suppliers and Price of Fmoc-L-tert-leucine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Fmoc-L-tert-leucine
10g
$ 358.00

TRC
Fmoc-Tle-OH
500mg
$ 70.00

TCI Chemical
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tert-leucine
5G
$ 44.00

TCI Chemical
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tert-leucine
25G
$ 132.00

Sigma-Aldrich
Fmoc-tBu-Gly-OH ≥98.0%
1g
$ 189.00

Sigma-Aldrich
Fmoc-α-t-butylglycine Novabiochem?
5 g
$ 554.00

Sigma-Aldrich
Fmoc-α-t-butylglycine Novabiochem . CAS 132684-60-7, molar mass 353.41 g/mol., Novabiochem
8520270005
$ 535.00

Sigma-Aldrich
Fmoc-α-t-butylglycine Novabiochem?
1 g
$ 140.00

Sigma-Aldrich
Fmoc-α-t-butylglycine Novabiochem . CAS 132684-60-7, molar mass 353.41 g/mol., Novabiochem
8520270001
$ 135.00

Oakwood
Fmoc-L-tert-leucine
1g
$ 10.00

Total 69 raw suppliers

Chemical Property of Fmoc-L-tert-leucine Edit

Chemical Property:

Appearance/Colour:White crystalline powder
Vapor Pressure:4.12E-13mmHg at 25°C
Melting Point:124-127 °C
Refractive Index:1.583
Boiling Point:554.1 °C at 760 mmHg
PKA:3.92±0.10(Predicted)
Flash Point:288.9 °C
PSA：75.63000
Density:1.209 g/cm³
LogP:4.41530
Storage Temp.:2-8°C
XLogP3:4.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:353.16270821
Heavy Atom Count:26
Complexity:505

Purity/Quality:

98%,99%, ^*data from raw suppliers

Fmoc-L-tert-leucine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Isomeric SMILES:CC(C)(C)[C@@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Uses Fmoc-Tle-OH is a versatile reactant used in the discovery of potent antagonists of antiapoptotic protein X-linked inhibitor of apoptosis (XIAP) for treatment of cancer. It is also used as reactant in the preparation of phosphino dipeptide derivatices as ligand in copper-phosphine catalyst for asymmetric conjugate addition of alkylzinc reagents to unsaturated ketones.

Technology Process of Fmoc-L-tert-leucine

There total 7 articles about Fmoc-L-tert-leucine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%