2-Amino-4-chlorobenzhydrol

Base Information

• Chemical Name: 2-Amino-4-chlorobenzhydrol
• CAS No.: 25648-19-5
• Molecular Formula: C₁₃H₁₂ClNO
• Molecular Weight: 233.697
• Mol file: 25648-19-5.mol

Synonyms:2-Amino-4-chlorobenzhydrol

Chemical Property of 2-Amino-4-chlorobenzhydrol

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Amino-4-chlorobenzhydrol

There total 5 articles about 2-Amino-4-chlorobenzhydrol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

2-amino-4-chlorobenzophenone (4076-50-0) → 2-Amino-4-chlorobenzhydrol (25648-19-5)

Guidance literature:

With sodium tetrahydroborate; In ethanol; for 2h; Heating;

DOI:10.1002/jhet.5570210432

Reference yield:

7-chloro-2-methyl-4H-3,1-benzoxazin-4-one (708-73-6) → 2-Amino-4-chlorobenzhydrol (25648-19-5)

Guidance literature:

Multi-step reaction with 3 steps

1: tetrahydrofuran

2: aq. HCl / ethanol

3: NaBH₄ / ethanol

With hydrogenchloride; sodium tetrahydroborate; In tetrahydrofuran; ethanol;

Reference yield:

N-(2-benzoyl-5-chlorophenyl)acetamide (34999-47-8) → 2-Amino-4-chlorobenzhydrol (25648-19-5)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. HCl / ethanol

2: NaBH₄ / ethanol

With hydrogenchloride; sodium tetrahydroborate; In ethanol;

upstream raw materials:

2-amino-4-chlorobenzophenone

7-chloro-2-methyl-4H-3,1-benzoxazin-4-one

N-(2-benzoyl-5-chlorophenyl)acetamide

Downstream raw materials:

7-chloro-2-methylsulfanyl-4-phenyl-4H-benzo[d][1,3]thiazine

8-Chloro-5-phenyl-5H-4-thia-3,9b-diaza-cyclopenta[a]naphthalene-2-carboxylic acid ethyl ester; hydrobromide

8-Chloro-5-phenyl-5H-4-thia-3,9b-diaza-cyclopenta[a]naphthalene-2-carboxylic acid

7-chloro-4-phenyl-1,4-dihydro-benzo[d][1,3]thiazine-2-thione

Refernces